J
Jacek Kijowski
Researcher at Jagiellonian University Medical College
Publications - 30
Citations - 2386
Jacek Kijowski is an academic researcher from Jagiellonian University Medical College. The author has contributed to research in topics: Haematopoiesis & Bone marrow. The author has an hindex of 14, co-authored 29 publications receiving 2220 citations. Previous affiliations of Jacek Kijowski include University of Pennsylvania & Pomeranian Medical University.
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Journal ArticleDOI
Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer.
Anna Janowska-Wieczorek,Marcin Wysoczynski,Marcin Wysoczynski,Jacek Kijowski,Jacek Kijowski,Leah A. Marquez-Curtis,Leah A. Marquez-Curtis,Bogdan Machalinski,Bogdan Machalinski,Janina Ratajczak,Janina Ratajczak,Mariusz Z. Ratajczak,Mariusz Z. Ratajczak +12 more
TL;DR: It is suggested that PMV play an important role in tumor progression/metastasis and angiogenesis in lung cancer.
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Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment
Anna Janowska-Wieczorek,Marcin Majka,Jacek Kijowski,Monika Baj-Krzyworzeka,Ryan Reca,A. Robert Turner,Janina Ratajczak,Steven G. Emerson,M. Anna Kowalska,Mariusz Z. Ratajczak +9 more
TL;DR: It was found that PMPs are more numerous on mPB than on BM CD34+ cells, do not affect the clonogenicity of human and murine HSPCs, and increase adhesion of these cells to endothelium and immobilized SDF-1, indicating a new role for PMPs in stem cell transplantation and may have clinical implications for the optimization of transplantations.
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Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells.
Monika Baj-Krzyworzeka,Marcin Majka,Domenico Praticò,Janina Ratajczak,Gaston Vilaire,Jacek Kijowski,Ryan Reca,Anna Janowska-Wieczorek,Mariusz Z. Ratajczak,Mariusz Z. Ratajczak +9 more
TL;DR: It is concluded that PMPs modulate biological functions of hematopoietic cells and postulate that they play an important but as yet not fully understood role in intercellular cross-talk in hematoiesis.
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Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV.
Tomasz Rozmyslowicz,Marcin Majka,Jacek Kijowski,Samuel J.H. Murphy,Dareus O. Conover,Mortimer Poncz,Janina Ratajczak,Glen N. Gaulton,Mariusz Z. Ratajczak +8 more
TL;DR: It is postulated that both PMP and MegaMP may play a novel and important role in spreading HIV-1 infection by transferring the CXCR4 co-receptor to CD4+/CX CR4-null cells.
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The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells.
Jacek Kijowski,Monika Baj-Krzyworzeka,Marcin Majka,Ryan Reca,Leah A. Marquez,Melpo Christofidou-Solomidou,Anna Janowska-Wieczorek,Anna Janowska-Wieczorek,Mariusz Z. Ratajczak +8 more
TL;DR: It is concluded that perturbation of the SDF‐1‐CXCR4 axis during HIV infection may affect interactions of hematopoietic cells with their microenvironment and does not directly influence their proliferation or survival.