L
Leah A. Marquez-Curtis
Researcher at University of Alberta
Publications - 50
Citations - 3250
Leah A. Marquez-Curtis is an academic researcher from University of Alberta. The author has contributed to research in topics: Progenitor cell & Stromal cell. The author has an hindex of 26, co-authored 49 publications receiving 2970 citations. Previous affiliations of Leah A. Marquez-Curtis include Canadian Blood Services & Pomeranian Medical University.
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Journal ArticleDOI
Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer.
Anna Janowska-Wieczorek,Marcin Wysoczynski,Marcin Wysoczynski,Jacek Kijowski,Jacek Kijowski,Leah A. Marquez-Curtis,Leah A. Marquez-Curtis,Bogdan Machalinski,Bogdan Machalinski,Janina Ratajczak,Janina Ratajczak,Mariusz Z. Ratajczak,Mariusz Z. Ratajczak +12 more
TL;DR: It is suggested that PMV play an important role in tumor progression/metastasis and angiogenesis in lung cancer.
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Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases.
Bo-Ra Son,Leah A. Marquez-Curtis,Magda Kucia,Marcin Wysoczynski,A. Robert Turner,Janina Ratajczak,Mariusz Z. Ratajczak,Anna Janowska-Wieczorek,Anna Janowska-Wieczorek +8 more
TL;DR: In vitro results suggest that the SDF‐1‐CXCR4 and HGF‐c‐met axes, along with MMPs, may be involved in recruitment of expanded MSCs to damaged tissues.
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Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects.
TL;DR: It is concluded that viable MSCs from diverse tissues can be recovered after cryopreservation using a variety of freezing protocols, cryoprotectants, storage periods and temperatures, and alterations in certain functions following cryop Reservation warrant future investigations on the recovery of cells post-thaw followed by expansion of functional cells.
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Enhancing the Migration Ability of Mesenchymal Stromal Cells by Targeting the SDF-1/CXCR4 Axis
TL;DR: Findings indicate that MSCs can be manipulated in vitro to enhance their in vivo recruitment and efficacy for tissue repair.
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Enhancing effect of platelet‐derived microvesicles on the invasive potential of breast cancer cells
TL;DR: It was hypothesized that PLT‐derived microvesicles interact with breast cancer cells, increasing their invasiveness.