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Jae Sik Yu

Researcher at Sungkyunkwan University

Publications -  65
Citations -  884

Jae Sik Yu is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: Chemistry & Withania somnifera. The author has an hindex of 13, co-authored 60 publications receiving 493 citations. Previous affiliations of Jae Sik Yu include Kangwon National University.

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Withaninsams A and B: Phenylpropanoid Esters from the Roots of Indian Ginseng (Withania somnifera)

TL;DR: This study is the first to report on phenylpropanoid esters with 4-methyl-1,4-pentanediol unit, and the anti-inflammatory mechanism through the inhibition of transcriptional iNOS protein expression was confirmed by western blotting experiments for the active compound 3, which showed decreased iNos protein expression.
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Lobatamunsolides A-C, Norlignans from the Roots of Pueraria lobata and their Nitric Oxide Inhibitory Activities in Macrophages.

TL;DR: Phytochemical investigation of the methanol (MeOH) extract of Pueraria lobata roots, known as “kudzu”, combined with liquid chromatography/mass spectrometry (LC/MS)-based analysis, resulted in the identification of four norlignans, including three new norlIGNans, lobatamunsolides A–C (1–3), and five known isoflavonoids (5–9).
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7α,15-Dihydroxydehydroabietic acid from Pinus koraiensis inhibits the promotion of angiogenesis through downregulation of VEGF, p-Akt and p-ERK in HUVECs

TL;DR: Experimental evidence of a novel biological activity of 7α,15-dihydroxydehydroabietic acid (5) as a potential antiangiogenic substance is provided and it is suggested that compound 5 could potentially be a useful adjuvant therapeutic substance for cancer prevention and treatment.
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Metabolite Profile of Cucurbitane-Type Triterpenoids of Bitter Melon (Fruit of Momordica charantia) and Their Inhibitory Activity against Protein Tyrosine Phosphatases Relevant to Insulin Resistance.

TL;DR: In this paper, a qualitative analysis of cucurbitane-type triterpenoids of bitter melon (fruit of Momordica charantia L.) using ultraperformance liquid chromatography quadrupole time-of-flight mass spectrometry revealed 27 promising cucurbitsane type triterbenoids.
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Antioxidant and Anti-Inflammatory Effects of White Mulberry (Morus alba L.) Fruits on Lipopolysaccharide-Stimulated RAW 264.7 Macrophages.

TL;DR: In this article, the protection of white mulberry (Morus alba) fruits on lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages was investigated.