S
Sil Kim
Researcher at Sungkyunkwan University
Publications - 13
Citations - 278
Sil Kim is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: Ginseng & Withania somnifera. The author has an hindex of 8, co-authored 13 publications receiving 206 citations.
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Journal ArticleDOI
Bioactivity-guided isolation of ginsenosides from Korean Red Ginseng with cytotoxic activity against human lung adenocarcinoma cells.
Jae Sik Yu,Hyun-Soo Roh,Kwan-Hyuck Baek,Seul Lee,Sil Kim,Hae Min So,Eunjung Moon,Changhyun Pang,Tae Su Jang,Ki-Hyun Kim +9 more
TL;DR: Bioactivity-guided fractionation of the KRG extract revealed that its ethyl acetate–soluble fraction exerts significant cytotoxic activity against all human lung cancer cell lines tested by inducing apoptosis, providing experimental evidence for a novel biological activity of ginsenoside Rg3 againsthuman lung cancer cells.
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Bioactivity evaluations of betulin identified from the bark of Betula platyphylla var. japonica for cancer therapy.
Hae Min So,Hee Jeong Eom,Dahae Lee,Sil Kim,Ki Sung Kang,Il Kyun Lee,Kwan-Hyuck Baek,Jun Yeon Park,Ki Hyun Kim +8 more
TL;DR: Findings provide the first experimental evidence for potential use of B. platyphylla var.
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LC/MS-based Analysis of Bioactive Compounds from the Bark of Betula platyphylla var. japonica and Their Effects on Regulation of Adipocyte and Osteoblast Differentiation
Su Cheol Baek,E. S. Choi,Hee Jeong Eom,Mun Seok Jo,Sil Kim,Hae Min So,Seon-Hee Kim,Ki Sung Kang,Ki-Hyun Kim +8 more
TL;DR: The results demonstrated that both compounds showed marginal inhibitory effects on adipocyte differentiation but did not affect osteoblast differentiation, and was the first study to demonstrate that the isolated compounds, 7-oxo-β- sitosterol and soyacerebroside I, were isolated in B. japonica.
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Cytotoxic Withanolides from the Roots of Indian Ginseng ( Withania somnifera).
TL;DR: Chemical investigation of the MeOH extract of W. somnifera roots combined with LC/MS-based analysis resulted in the identification of six new withanolides, withasilolides A-F (1-6), as well as seven known compounds (7-13).
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Bioactivity-based analysis and chemical characterization of anti-inflammatory compounds from Curcuma zedoaria rhizomes using LPS-stimulated RAW264.7 cells
Tae Kyoung Lee,Tuy An Trinh,Seoung Rak Lee,Sil Kim,Hae Min So,Eunjung Moon,Gwi Seo Hwang,Ki Sung Kang,Jihwan Kim,Noriko Yamabe,Ki-Hyun Kim +10 more
TL;DR: Curcuzedoalide (5) was determined to be a contributor to the anti-inflammatory effect of C. zedoaria rhizomes and could be a potential candidate for therapeutic applications.