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Jae Sik Yu

Researcher at Sungkyunkwan University

Publications -  65
Citations -  884

Jae Sik Yu is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: Chemistry & Withania somnifera. The author has an hindex of 13, co-authored 60 publications receiving 493 citations. Previous affiliations of Jae Sik Yu include Kangwon National University.

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Vulpinic acid contributes to the cytotoxicity of Pulveroboletus ravenelii to human cancer cells by inducing apoptosis

TL;DR: This study explored the pharmacological activity of the fruiting bodies of P. ravenelii and found that their MeOH extracts showed cytotoxic activity in vitro against a variety of human cancer cells, and identified vulpinic acid (VA) as the main component of the most cytot toxic fraction, the hexane-soluble fraction.
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Potential Anti-Skin Aging Effect of (-)-Catechin Isolated from the Root Bark of Ulmus davidiana var. japonica in Tumor Necrosis Factor-α-Stimulated Normal Human Dermal Fibroblasts.

TL;DR: In this paper, the potential anti-skin aging effect of (-)-phenolic compounds isolated from the root bark of Ulmus davidiana var. japonica was evaluated, and (-)-catechin is a candidate to ameliorate both intrinsic and extrinsic skin aging.
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Ergopyrone, a Styrylpyrone-Fused Steroid with a Hexacyclic 6/5/6/6/6/5 Skeleton from a Mushroom Gymnopilus orientispectabilis.

TL;DR: A styrylpyrone-fused ergosterol derivative, ergopyrone (1), was isolated and structurally characterized from a mushroom, Gymnopilus orientispectabilis, along with five biosynthetically related metabolites as mentioned in this paper.
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Identification of Anti-Inflammatory Compounds from Hawaiian Noni (Morinda citrifolia L.) Fruit Juice

TL;DR: Data demonstrated that compounds 1–5 present in noni fruit juice, exhibited potential anti-inflammatory activity; these active compounds may contribute preventively and therapeutically against inflammatory diseases.
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Antidiabetic Flavonoids from Fruits of Morus alba Promoting Insulin-Stimulated Glucose Uptake via Akt and AMP-Activated Protein Kinase Activation in 3T3-L1 Adipocytes.

TL;DR: In this paper, the authors investigated the antidiabetic properties of the white mulberry (Morus alba) fruits using 3T3-L1 adipocytes and found that rutin and quercetin improved glucose uptake via Akt-mediated insulin signaling pathway or AMP-activated protein kinase (AMPK) activation.