J
James A. McKinnell
Researcher at UCLA Medical Center
Publications - 98
Citations - 3097
James A. McKinnell is an academic researcher from UCLA Medical Center. The author has contributed to research in topics: Methicillin-resistant Staphylococcus aureus & Population. The author has an hindex of 27, co-authored 91 publications receiving 2390 citations. Previous affiliations of James A. McKinnell include Los Angeles County Department of Public Health & Memorial Medical Center.
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Journal ArticleDOI
The Potential Health Care Costs And Resource Use Associated With COVID-19 In The United States.
Sarah M. Bartsch,Marie C. Ferguson,James A. McKinnell,Kelly J. O'Shea,Patrick T. Wedlock,Sheryl S. Siegmund,Bruce Y. Lee +6 more
TL;DR: A Monte Carlo simulation model representing the U.S. population and what can happen to each person who gets infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is developed to understand the potential economic benefits of reducing the burden of the disease.
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Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention.
Sarah M. Bartsch,Kelly J. O'Shea,Marie C. Ferguson,Maria Elena Bottazzi,Patrick T. Wedlock,Ulrich Strych,James A. McKinnell,Sheryl S. Siegmund,Sarah N. Cox,Peter J. Hotez,Bruce Y. Lee +10 more
TL;DR: This study found that the vaccine has to have an efficacy of at least 70% to prevent an epidemic and at least 80% to largely extinguish an epidemic without any other measures (e.g., social distancing).
Journal ArticleDOI
Carotenoid-Related Alteration of Cell Membrane Fluidity Impacts Staphylococcus aureus Susceptibility to Host Defense Peptides
Nagendra N. Mishra,George Y. Liu,George Y. Liu,Michael R. Yeaman,Cynthia C. Nast,Cynthia C. Nast,Richard A. Proctor,James A. McKinnell,Arnold S. Bayer +8 more
TL;DR: The concept that carotenoid biosynthesis can contribute to the ability of S. aureus to subvert nonoxidative host defenses mediated by cationic peptides is supported, potentially by increasing target membrane rigidity.
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Potential economic burden of carbapenem-resistant Enterobacteriaceae (CRE) in the United States
Sarah M. Bartsch,James A. McKinnell,Leslie E Mueller,Loren G. Miller,Shruti K. Gohil,Susan S. Huang,Bruce Y. Lee +6 more
TL;DR: A CRE clinical and economics outcomes model is developed to determine the cost of CRE infection from the hospital, third-party payer, and societal, perspectives and to evaluate the health and economic burden of CRE to the USA.
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Vital Signs: Estimated Effects of a Coordinated Approach for Action to Reduce Antibiotic-Resistant Infections in Health Care Facilities - United States.
Rachel B. Slayton,Damon J.A. Toth,Bruce Y. Lee,Windy Tanner,Sarah M. Bartsch,Karim Khader,Kim F. Wong,Kevin A. Brown,James A. McKinnell,William J. Ray,Loren G. Miller,Michael Rubin,Diane S. Kim,Frederick R. Adler,Chenghua Cao,Lacey Avery,Nathan T.B. Stone,Alexander J. Kallen,Matthew H. Samore,Susan S. Huang,Scott K. Fridkin,John A. Jernigan +21 more
TL;DR: Immediate nationwide infection control and antibiotic stewardship interventions, over 5 years, could avert an estimated 619,000 HAIs resulting from CRE, multidrug-resistant Pseudomonas aeruginosa, invasive methicillin-resistant Staphylococcus aureus (MRSA), or C. difficile.