J
James Champion
Researcher at University of North Carolina at Chapel Hill
Publications - 12
Citations - 142
James Champion is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: LOINC & Human Phenotype Ontology. The author has an hindex of 5, co-authored 8 publications receiving 67 citations.
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Journal ArticleDOI
Fast Healthcare Interoperability Resources (FHIR) as a Meta Model to Integrate Common Data Models: Development of a Tool and Quantitative Validation Study
Emily R. Pfaff,James Champion,Robert L. Bradford,Marshall Clark,Hao Xu,Karamarie Fecho,Ashok Krishnamurthy,Steven Cox,Christopher G. Chute,Casey Overby Taylor,Stan Ahalt +10 more
TL;DR: It is believed that CAMP FHIR can serve as an alternative to implementing new CDMs on a project-by-project basis and could support rare data sharing opportunities, such as collaborations between academic medical centers and community hospitals.
Journal ArticleDOI
Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery
Xingmin Aaron Zhang,Amy Yates,Nicole Vasilevsky,Jean-Philippe F. Gourdine,Tiffany J. Callahan,Leigh C. Carmody,Daniel Danis,Marcin P. Joachimiak,Vida Ravanmehr,Emily R. Pfaff,James Champion,Kimberly Robasky,Hao Xu,Karamarie Fecho,Nephi A. Walton,Richard L. Zhu,Justin Ramsdill,Christopher J. Mungall,Sebastian Köhler,Melissa A. Haendel,Melissa A. Haendel,Clement J. McDonald,Daniel J. Vreeman,Daniel J. Vreeman,David B. Peden,Tellen D. Bennett,James A. Feinstein,Blake Martin,Adrianne L. Stefanski,Lawrence Hunter,Christopher G. Chute,Peter N. Robinson +31 more
TL;DR: This work provides a method for mapping LOINC-encoded laboratory test results transmitted in FHIR standards to Human Phenotype Ontology (HPO) terms and annotated the medical implications of 2923 commonly used laboratory tests with HPO terms.
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Sex, Obesity, Diabetes, and Exposure to Particulate Matter among Patients with Severe Asthma: Scientific Insights from a Comparative Analysis of Open Clinical Data Sources during a Five-day Hackathon
Karamarie Fecho,Stanley C. Ahalt,Saravanan Arunachalam,James Champion,Christopher G. Chute,Sarah E.H. Davis,Kenneth R. Gersing,Gustavo Glusman,Jennifer Hadlock,Jewel Y Lee,Emily R. Pfaff,Max Robinson,Eric Sid,Casey N. Ta,Hao Xu,Richard L. Zhu,Qian Zhu,David B. Peden +17 more
TL;DR: The Translator team members self-organized and worked together to conceptualize and execute a multi-institutional clinical research study that aimed to examine, using open clinical data sources, relationships between sex, obesity, diabetes, and exposure to airborne fine particulate matter among patients with severe asthma.
Journal ArticleDOI
A novel approach for exposing and sharing clinical data: the Translator Integrated Clinical and Environmental Exposures Service.
Karamarie Fecho,Emily R. Pfaff,Hao Xu,James Champion,Steve Cox,Lisa Stillwell,David B. Peden,Chris Bizon,Ashok Krishnamurthy,Alexander Tropsha,Stanley C. Ahalt +10 more
TL;DR: The preliminary evaluation results demonstrate a relationship between exposure to high levels of particulate matter ≤2.5 µm in diameter and the frequency of emergency department or inpatient visits for respiratory issues and validated the overall approach for openly exposing and sharing integrated clinical and environmental exposures data.
Journal ArticleDOI
FHIR PIT: an open software application for spatiotemporal integration of clinical data and environmental exposures data.
Hao Xu,Steven Cox,Lisa Stillwell,Emily R. Pfaff,James Champion,Stanley C. Ahalt,Karamarie Fecho +6 more
TL;DR: While FHIR PIT was developed to support a driving use case on asthma, the software can be used to integrate any type and number of spatiotemporal data sources at a level of granularity that enables individual-level study.