E
Emily R. Pfaff
Researcher at University of North Carolina at Chapel Hill
Publications - 72
Citations - 1328
Emily R. Pfaff is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 12, co-authored 33 publications receiving 397 citations.
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Journal ArticleDOI
The National COVID Cohort Collaborative (N3C): Rationale, Design, Infrastructure, and Deployment.
Melissa A. Haendel,Melissa A. Haendel,Christopher G. Chute,Tellen D. Bennett,David Eichmann,Justin Guinney,Warren A. Kibbe,Philip R. O. Payne,Emily R. Pfaff,Peter N. Robinson,Joel H. Saltz,Heidi Spratt,Christine Suver,John Wilbanks,Adam B. Wilcox,Andrew E. Williams,Chunlei Wu,Clair Blacketer,Robert L. Bradford,James J. Cimino,Marshall Clark,Evan W Colmenares,Patricia A Francis,Davera Gabriel,Alexis Graves,Raju Hemadri,Stephanie S Hong,George Hripscak,Dazhi Jiao,Jeffrey G. Klann,Kristin Kostka,Adam M Lee,Harold P Lehmann,Lora Lingrey,Robert T. Miller,Michele I. Morris,Shawn N. Murphy,Karthik Natarajan,Matvey B. Palchuk,Usman Sheikh,Harold R. Solbrig,Shyam Visweswaran,Anita Walden,Anita Walden,Kellie M Walters,Griffin M. Weber,Xiaohan Tanner Zhang,Richard L Zhu,Benjamin Amor,Andrew T Girvin,Amin Manna,Nabeel Qureshi,Michael G. Kurilla,Sam Michael,Lili M Portilla,Joni L Rutter,Christopher P. Austin,Ken R Gersing +57 more
TL;DR: The N3C has demonstrated that a multisite collaborative learning health network can overcome barriers to rapidly build a scalable infrastructure incorporating multiorganizational clinical data for COVID-19 analytics.
Journal ArticleDOI
Characterizing Long COVID: Deep Phenotype of a Complex Condition
Rachel R Deer,Madeline A Rock,Nicole Vasilevsky,Leigh C. Carmody,Halie M. Rando,Alfred J. Anzalone,Marc D. Basson,Tellen D. Bennett,Timothy Bergquist,Eilis A. Boudreau,Carolyn T. Bramante,James Brian Byrd,Tiffany J. Callahan,Lauren E Chan,Haitao Chu,Christopher G. Chute,Ben Coleman,Hannah E. Davis,Joel J. Gagnier,Casey S. Greene,William B. Hillegass,Ramakanth Kavuluru,Wesley Kimble,Farrukh M. Koraishy,Sebastian Köhler,Chen Liang,Feifan Liu,Hongfang Liu,Vithal Madhira,Charisse R. Madlock-Brown,Nicolas Matentzoglu,Diego R. Mazzotti,Julie A. McMurry,Douglas S McNair,Richard A. Moffitt,Teshamae S. Monteith,Ann M. Parker,Mallory A Perry,Emily R. Pfaff,Justin T. Reese,Joel H. Saltz,Robert A Schuff,Anthony Solomonides,Julian Solway,Heidi Spratt,Gary S. Stein,Anupam A Sule,Umit Topaloglu,George D. Vavougios,Liwei Wang,Melissa Haendel,Peter N. Robinson +51 more
TL;DR: In this article, the authors identified 303 articles published before April 29, 2021, curated 59 relevant manuscripts that described clinical manifestations in 81 cohorts three weeks or more following acute COVID-19, and mapped 287 unique clinical findings to HPO terms.
Posted ContentDOI
Challenges in defining Long COVID: Striking differences across literature, Electronic Health Records, and patient-reported information
Halie M. Rando,Halie M. Rando,Tellen D. Bennett,James Brian Byrd,Carolyn T. Bramante,Tiffany J. Callahan,Christopher G. Chute,Hannah E. Davis,Rachel R Deer,Joel Gagnier,Farrukh M. Koraishy,Feifan Liu,Julie A. McMurry,Richard A. Moffitt,Emily R. Pfaff,Justin T. Reese,Rose Relevo,Peter N. Robinson,Joel H. Saltz,Anthony Solomonides,Anupam A Sule,Umit Topaloglu,Melissa Haendel +22 more
TL;DR: In this article, the authors investigate the definitions used in the literature published to date and compare them against data available from electronic health records and patient-reported information collected via surveys, and conclude that Long COVID holds the potential to produce a second public health crisis on the heels of the pandemic itself.
Journal ArticleDOI
Characteristics, Outcomes, and Severity Risk Factors Associated With SARS-CoV-2 Infection Among Children in the US National COVID Cohort Collaborative
Blake Martin,Peter E. DeWitt,Seth Russell,A. Anand,Katie Bradwell,C. Bremer,Davera Gabriel,Andrew T. Girvin,Janos Hajagos,Julie A. McMurry,Andrew J. Neumann,Emily R. Pfaff,Anita Walden,Jacob T. Wooldridge,Yung Jae Yoo,Joel H. Saltz,Kenneth Gersing,Christopher G. Chute,Melissa A. Haendel,Richard A. Moffitt,Tellen D. Bennett +20 more
TL;DR: Several demographic and comorbidity variables and many initial vital sign and laboratory test values were associated with higher peak illness severity and could assist with early identification of children at risk for severe disease due to SARS-CoV-2 infection.
Journal ArticleDOI
Identifying who has long COVID in the USA: a machine learning approach using N3C data
Emily Niehaus,Emily R. Pfaff +1 more
TL;DR: In this article , the authors developed XGBoost machine learning models to identify potential patients with long co-virus infection, which is characterized by evolving, heterogeneous symptoms, making it challenging to derive an unambiguous definition.