J
James E. Korkola
Researcher at Oregon Health & Science University
Publications - 100
Citations - 16516
James E. Korkola is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 34, co-authored 89 publications receiving 14360 citations. Previous affiliations of James E. Korkola include University of Toronto & Kettering University.
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Journal ArticleDOI
Development and Validation of a Gene-Based Model for Outcome Prediction in Germ Cell Tumors Using a Combined Genomic and Expression Profiling Approach
James E. Korkola,Sandy Heck,Adam B. Olshen,Darren R. Feldman,Victor E. Reuter,Jane Houldsworth,George J. Bosl,Raju S.K. Chaganti,Raju S.K. Chaganti +8 more
TL;DR: A combined genomic and expression profiling approach to identify genomic regions and underlying genes that are predictive of outcome in GCT patients and indicates that these genes may aid in the identification of the small subset of patients who are at high risk of poor outcome.
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Using Microarrays to Interrogate Microenvironmental Impact on Cellular Phenotypes in Cancer.
Rebecca Smith,Kaylyn Devlin,David Kilburn,Sean M. Gross,Damir Sudar,Elmar Bucher,Michel Nederlof,Mark A. Dane,Joe W. Gray,Laura M. Heiser,James E. Korkola +10 more
TL;DR: Analysis of the breast cancer cell line MCF7 was plated on the MEMA platform and factors that both enhance and inhibit the growth and proliferation of these cells were identified.
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Resistance to chemically-induced mammary tumors in Copenhagen x nude-derived F2 athymic rats: Evidence that T-cell immunity is not involved in Copenhagen resistance
TL;DR: Results indicate that T-cells are not involved in Cop resistance, and that nude rats are resistant to N-methyl-N-nitrosourea-induced mammary tumorigenesis.
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A multiplex implantable microdevice assay identifies synergistic combinations of cancer immunotherapies and conventional drugs
Zuzana Tatárová,Dylan C. Blumberg,James E. Korkola,Laura M. Heiser,John Muschler,Pepper Schedin,Sebastian W. Ahn,Gordon B. Mills,Lisa M. Coussens,Oliver Jonas,Joe W. Gray +10 more
TL;DR: In this article , the authors integrated high-throughput and high-content techniques to investigate the tumor cell and immunological response signatures to different treatment regimens, and identified effective combinations from among numerous agents within days.
Journal ArticleDOI
Optimizing stringency for expression microarrays
James E. Korkola,Anne L. Estep,Sunanda Pejavar,Sandy DeVries,Ronald H. Jensen,Frederic M. Waldman +5 more
TL;DR: Analysis of a series of cell lines washed at the optimized stringency indicated that the rank order of relative expression levels for ERBB2 microarray clones agreed well with theRank order of ERBB1 levels, as measured by quantitative PCR.