James F. Hejtmancik

TL;DR: A series of regression models were fitted to estimate the proportion of moderate or severe vision impairment and blindness by cause, age, region, and year, and found that world regions varied markedly in the causes of blindness and vision impairment in this age group.

TL;DR: There is an ongoing reduction in the age-standardised prevalence of blindness and visual impairment, yet the growth and ageing of the world's population is causing a substantial increase in number of people affected, highlighting the need to scale up vision impairment alleviation efforts at all levels.

TL;DR: It is reported here that many forms of age‐dependent change, including alterations in heart, liver, adrenal glands, endometrium, and tendon, as well as age-dependent decline in spontaneous activity, occur more slowly in rapamycin‐treated mice, suggesting strongly thatRapamycin retards multiple aspects of aging in mice, in addition to any beneficial effects it may have on neoplastic disease.

TL;DR: It is established that MsrA is present throughout the human lens, where it is likely to defend lens cells and their components against methionine oxidation, and evidence that MsRA is important for lens cell function in the absence of exogenous stress is provided.

TL;DR: Observations suggest that the observed mutation might be causally related to the cataracts in this family.