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James H. Morrissey

Researcher at University of Michigan

Publications -  278
Citations -  20534

James H. Morrissey is an academic researcher from University of Michigan. The author has contributed to research in topics: Tissue factor & Factor VII. The author has an hindex of 62, co-authored 261 publications receiving 18947 citations. Previous affiliations of James H. Morrissey include Queen Mary University of London & University of California, San Diego.

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Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity

James H. Morrissey
- 01 Nov 1981 - 
TL;DR: It was found that treatment of gels with dithiothreitol prior to impregnation with silver nitrate results in more reproducible staining patterns that are also qualitatively similar to those obtained with Coomassie blue.
Journal Article

Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis.

Thomas A. Drake, +2 more
- 01 May 1989 - 
TL;DR: It is hypothesized that intrav vascular initiation of coagulation requires induced expression by intravascular cells, and that the normal distribution of TF represents a hemostatic "envelope" ready to activate coagulations when vascular integrity is disrupted.
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Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo

Felicitas Müller, +9 more
- 11 Dec 2009 - 
TL;DR: The data identify polyP as a new class of mediator having fundamental roles in platelet-driven proinflammatory and procoagulant disorders, including Hermansky-Pudlak Syndrome patients, who lack platelet polyP.
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Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

Fabrizio Semeraro, +6 more
- 18 Aug 2011 - 
TL;DR: Data show that histone-activated platelets possess a procoagulant phenotype that drives plasma thrombin generation and suggest that TLR2 and TLR4 mediate the activation process.
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Activated platelets signal chemokine synthesis by human monocytes.

Andrew S. Weyrich, +11 more
- 15 Mar 1996 - 
TL;DR: Thrombin-activated platelets induce the expression and secretion of monocyte chemotactic protein-1 and IL-8 by monocytes and provide a model for the study of gene regulation in cell-cell interactions, suggesting that activated platelets regulate chemokine secretion by monocyte in inflammatory lesions in vivo.