J
James Jeffrey Bradstreet
Researcher at Southwest College of Naturopathic Medicine
Publications - 15
Citations - 1398
James Jeffrey Bradstreet is an academic researcher from Southwest College of Naturopathic Medicine. The author has contributed to research in topics: Autism & Stem cell. The author has an hindex of 15, co-authored 15 publications receiving 1290 citations.
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Journal ArticleDOI
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
S. Jill James,Stepan Melnyk,Stefanie Jernigan,Mario A. Cleves,Charles H. Halsted,Donna H. Wong,Paul Cutler,Kenneth Bock,Marvin Boris,James Jeffrey Bradstreet,Sidney M. Baker,David W. Gaylor +11 more
TL;DR: It is proposed that an increased vulnerability to oxidative stress (endogenous or environmental) may contribute to the development and clinical manifestations of autism.
A Case-Control Study of Mercury Burden in Children with Autistic Spectrum Disorders
TL;DR: Regardless of the mechanism by which children with autistic spectrum disorders have high urinary mercury concentrations, the DMSA treatment described in this study might be useful to diagnose their present burden of mercury.
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The severity of autism is associated with toxic metal body burden and red blood cell glutathione levels.
James B. Adams,Matthew Baral,Elizabeth Geis,Jessica Mitchell,Julie Ingram,A. Hensley,I. Zappia,Sanford Newmark,Eva Gehn,Robert A. Rubin,K. Mitchell,James Jeffrey Bradstreet,Jane Maroney El-Dahr +12 more
TL;DR: A significant positive association is demonstrated between the severity of autism and the relative body burden of toxic metals and the level of RBC glutathione.
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Cannabinoid Receptor Type 2, but Not Type 1, Is Up-Regulated in Peripheral Blood Mononuclear Cells of Children Affected by Autistic Disorders.
Dario Siniscalco,Anna Sapone,Anna Sapone,Catia Giordano,Alessandra Cirillo,Laura de Magistris,Francesco Rossi,Alessio Fasano,James Jeffrey Bradstreet,Sabatino Maione,Nicola Antonucci +10 more
TL;DR: The data indicate CB2 receptor as potential therapeutic target for the pharmacological management of the autism care, and the involvement of cannabinoid system in PBMCs from autistic children compared to age-matched normal healthy developing controls.
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Epigenetic findings in autism: new perspectives for therapy.
TL;DR: Bettering the understanding of how these gene-environmental interactions create autistic symptoms should facilitate the development of therapeutic targeting of gene expression for ASD biomedical care.