J
James W. Fawcett
Researcher at University of Cambridge
Publications - 357
Citations - 38704
James W. Fawcett is an academic researcher from University of Cambridge. The author has contributed to research in topics: Axon & Perineuronal net. The author has an hindex of 100, co-authored 350 publications receiving 35525 citations. Previous affiliations of James W. Fawcett include University of Sheffield & King's College London.
Papers
More filters
Journal ArticleDOI
Chondroitinase ABC promotes functional recovery after spinal cord injury
Elizabeth J. Bradbury,Lawrence D. F. Moon,Lawrence D. F. Moon,Reena J Popat,V.R. King,GS Bennett,Preena N. Patel,James W. Fawcett,Stephen B. McMahon +8 more
TL;DR: It is demonstrated that CSPGs are important inhibitory molecules in vivo and suggested that their manipulation will be useful for treatment of human spinal injuries.
Journal ArticleDOI
The glial scar and central nervous system repair
TL;DR: Deyelinated plaques in multiple sclerosis consists mostly of scar-type astrocytes and naked axons, but astroCytes inhibit the migration of both oligodendrocyte precursors and Schwann cells which must restrict their access to demyelinated axons.
Journal ArticleDOI
Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex
Tommaso Pizzorusso,Paolo Medini,Nicoletta Berardi,Sabrina Chierzi,James W. Fawcett,Lamberto Maffei +5 more
TL;DR: The mature ECM is thus inhibitory for experience-dependent plasticity, and degradation of CSPGs reactivates cortical plasticity.
Journal ArticleDOI
Regressive events in neurogenesis
TL;DR: Far from being relatively minor aspects of neural development, regressive phenomena are now recognized as playing a major role in determining the form of the mature nervous system.
PatentDOI
Peripheral nerve regeneration
James W. Fawcett,Roger J. Keynes +1 more
TL;DR: Basal lamina grafts for reconnecting severed nerves are prepared from muscle by removing cellular material therefrom while preserving the tubular structure of the basal lamina, eventually reestablishing nerve function through the regenerated graft.