J
Jamie Triccas
Researcher at University of Sydney
Publications - 6
Citations - 91
Jamie Triccas is an academic researcher from University of Sydney. The author has contributed to research in topics: Immunity & Innate immune system. The author has an hindex of 2, co-authored 6 publications receiving 38 citations.
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Journal ArticleDOI
Rifapentine-loaded PLGA microparticles for tuberculosis inhaled therapy: Preparation and in vitro aerosol characterization.
Thaigarajan Parumasivam,Sharon S.Y. Leung,Diana Huynh Quan,Jamie Triccas,Warwick J. Britton,Hak-Kim Chan +5 more
TL;DR: The monomer ratio and MW are not crucial in determining the aerosol performance and cytotoxicity profile of PLGA however, the particles with high lactide composition have a superior tendency for macrophage uptake.
Journal ArticleDOI
Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection.
Lei Li,Yoshikazu Honda-Okubo,Ying Huang,Hyesun Jang,Michael A. Carlock,Jeremy Baldwin,Sakshi Piplani,Anne G. Bebin-Blackwell,David Forgacs,Kaori Sakamoto,Alberto Ospina Stella,Stuart Turville,Tim Chataway,Alex D. Colella,Jamie Triccas,Ted M. Ross,Nikolai Petrovsky +16 more
TL;DR: Covax-19 as discussed by the authors is a recombinant spike protein vaccine that was developed for the SARS-CoV-2 pandemic using a synthetic gene encoding the spike extracellular domain (ECD) to express the protein in insect cell cultures.
Journal ArticleDOI
Synthesis and Characterization of pH-Sensitive Inulin Conjugate of Isoniazid for Monocyte-Targeted Delivery
Franklin Afinjuomo,Thomas G. Barclay,Ankit Parikh,Rosa Chung,Yunmei Song,Gayathri Nagalingam,Jamie Triccas,Lixin Wang,Liang Liu,John D. Hayball,Nikolai Petrovsky,Sanjay Garg +11 more
TL;DR: Inulin conjugates can serve as a pH-sensitive intracellular drug delivery system for TB treatment and demonstrate a dose-dependent targeting effect against Mtb-infected monocytes.
Posted ContentDOI
Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection
Lei Li,Yoshikazu Honda-Okubo,Ying Huang,Hyesun Jang,Michael A. Carlock,Jeremy Baldwin,Sakshi Piplani,Anne G. Bebin-Blackwell,David Forgacs,Kaori Sakamoto,Alberto Ospina Stella,Stuart Turville,Tim Chataway,Alex D. Colella,Jamie Triccas,Ted M. Ross,Nikolai Petrovsky +16 more
TL;DR: In this paper, a recombinant spike protein vaccine (Covax-19) was proposed for the SARS-CoV-2 pandemic, which was formulated with Advax-SM adjuvant and tested in C57BL/6 and BALB/c mice.
Posted ContentDOI
Rough and smooth variant Mycobacterium abscessus infections are differentially controlled by host immunity during chronic infection
Elinor Hortle,Julia Y Kam,E. Krogman,S. E. Warner,Kaiming Luo,Tina Cheng,Pradeep Manuneedhi Cholan,Kazu Kikuchi,Kazu Kikuchi,Jamie Triccas,Warwick J. Britton,Johansen,L. Kremer,L. Kremer,Stefan H. Oehlers +14 more
TL;DR: In this article, the authors used intraperitoneal infection of adult zebrafish to model M. abscessus pathogenesis in the context of fully functioning host immunity and found infection with the R variant penetrates host organs causing an inflammatory immune response leading to necrotic granuloma formation within 2 weeks.