Ted M. Ross

TL;DR: Data support targeting IL-17 orIL-17RA in acute lung injury due to acute viral infection and shows significantly reduced levels of oxidized phospholipids, which have previously been shown to be an important mediator in several models of acute Lung injury, including influenza infection and gastric acid aspiration.

TL;DR: Interestingly, VLPs elicited antibodies that recognized a broader panel of antigenically distinct H3N2 viral isolates compared to rHA or WIV in a hemagglutination-inhibition (HAI) assay.

TL;DR: High-resolution proteomics analysis of immunoglobulin coupled with high-throughput sequencing of transcripts encoding B cell receptors to quantitatively determine the antibody repertoire at the individual clonotype level in the sera of young adults before and after vaccination with trivalent seasonal influenza vaccine reveals unanticipated insights regarding the serological response to influenza vaccination.

TL;DR: The results show that a non-replicating virus-like particle is effective at eliciting a broadened, cross-clade protective immune response to proteins from emerging H5N1 influenza isolates giving rise to a potential pandemic influenza vaccine candidate for humans that can be stockpiled for use in the event of an outbreak of H5n1 influenza.

TL;DR: In this paper, the authors defined correlates of protection of neutralizing human monoclonal antibodies (mAbs) in SARS-CoV-2-infected animals.