J
Janet L. Maryanski
Researcher at Ludwig Institute for Cancer Research
Publications - 68
Citations - 4366
Janet L. Maryanski is an academic researcher from Ludwig Institute for Cancer Research. The author has contributed to research in topics: Antigen & CTL*. The author has an hindex of 34, co-authored 68 publications receiving 4326 citations. Previous affiliations of Janet L. Maryanski include Claude Bernard University Lyon 1 & French Institute of Health and Medical Research.
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Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria
Pedro Romero,Janet L. Maryanski,Giampietro Corradin,Ruth S. Nussenzweig,Victor Nussenzweig,Fidel Zavala +5 more
TL;DR: In this article, an epitope contained within amino acids 249-260 of the Plasmodium berghei circumsporozoite protein was identified by H-2Kd-restricted cytotoxic T cells.
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Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation
Maria Ciofani,Thomas M. Schmitt,Amelia Ciofani,Alison M. Michie,Nicolas Çuburu,Anne Aublin,Janet L. Maryanski,Juan Carlos Zúñiga-Pflücker +7 more
TL;DR: It is shown that pre-TCR signaling concurrent with Notch receptor and Delta-like-1 ligand interactions are required for the survival, proliferation, and differentiation of mouse CD4−CD8− thymocytes to the CD4+CD8+ stage.
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Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression.
TL;DR: Four different tumor-associated antigenic specificities were defined, each recognized by a specific CTL clone, one of which was absent from all escaping tumor cells and another had been lost by some of them.
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H—2-restricted cytolytic T cells specific for HLA can recognize a synthetic HLA peptide
TL;DR: These anti-HLA CTL clones can lyse HLA-negative syngeneic mouse cells in the presence of a synthetic HLA peptide, suggesting that the model applies generally to viral proteins that are expressed internally and to antigens normally expressed as integral membrane proteins at the cell surface.
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CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria
Mauricio M. Rodrigues,Anne Sophie Cordey,Gladys Arreaza,Giampetro Corradin,Pedro Romero,Janet L. Maryanski,Ruth S. Nussenzweig,Fidel Zavala +7 more
TL;DR: Using P. yoelii specific ribosomal RNA probes to monitor the in vivo effects of the CTL clones, it was found that their target was the intrahepatocytic stage of the parasite.