Janneth Gonzalez

TL;DR: The main purpose has been to consider a large scale population, with statistical significance, in a real multimodal procedure, and including several sources of variability that can be found in real environments.

TL;DR: The implications of astrocyte functions in the protection of the blood–brain barrier, and in the development of Parkinson’s disease (PD) and related disorders are discussed.

TL;DR: The aim of this paper is to present various well-known dietary polyphenols and their mechanisms of neuroprotection with an emphasis on Alzheimer’s disease, Parkinson's disease, and amyotrophic lateral sclerosis.

TL;DR: This review will focus on astrocytic activities that can both protect and endanger neurons, and discuss how manipulating these functions provides a novel and important strategy to enhance neuronal survival and improve the outcome following brain injury.

TL;DR: The mechanisms by which polyphenols and endogenous antioxidants can produce protection against oxidative stress are reviewed, including: scavenging nitrogen and oxygen reactive species, regulation of signaling pathways associated with cell survival and inflammation, and inhibition of synphilin-1 and alpha-synuclein aggregation.