J
Javier A. Menendez
Researcher at NorthShore University HealthSystem
Publications - 336
Citations - 29348
Javier A. Menendez is an academic researcher from NorthShore University HealthSystem. The author has contributed to research in topics: Cancer & Fatty acid synthase. The author has an hindex of 73, co-authored 317 publications receiving 25654 citations. Previous affiliations of Javier A. Menendez include Northwestern University & Boston Biomedical Research Institute.
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Journal ArticleDOI
Metformin: a cheap and well-tolerated drug that provides benefits for viral infections.
Jorge Joven,Javier A. Menendez,Laura Fernández-Sender,Eugenia Espinel,Anna Rull,Raúl Beltrán-Debón,Esther Rodríguez-Gallego,Marta Riera-Borrull,Juan Pedro-Botet,Carlos Alonso-Villaverde,Jordi Camps,Gerard Aragonès +11 more
TL;DR: The effectiveness of metformin for alleviating insulin resistance in HIV‐infected patients is explored and the relevance of the ataxia‐telangiectasia mutated (ATM) rs11212617 variant in the clinical response is assessed with the rationale that met formin modulates cellular bioenergetics in an ATM‐dependent process.
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Discovery and validation of an INflammatory PROtein-driven GAstric cancer Signature (INPROGAS) using antibody microarray-based oncoproteomics
Manuel Puig-Costa,Antonio Codina-Cazador,Elisabet Cortés-Pastoret,Cristina Oliveras-Ferraros,Sílvia Cufí,Silvia Flaquer,Francesca Llopis-Puigmarti,Eulalia Pujol-Amado,Bruna Corominas-Faja,Elisabet Cuyàs,Rosa Ortiz,Eugeni López-Bonet,Bernardo Queralt,Raquel Guardeño,Begoña Martin-Castillo,Josep Roig,Jorge Joven,Javier A. Menendez +17 more
TL;DR: Antibody microarray analyses of the GC-associated inflammatory proteome identified a 21-protein INPROGAS that accurately discriminated GC from noncancerous gastric mucosa.
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Evolution of the predictive markers amphiregulin and epiregulin mRNAs during long-term cetuximab treatment of KRAS wild-type tumor cells
Cristina Oliveras-Ferraros,Anna Massaguer Vall-llovera,Dolors Carrion Salip,Alejandro Vazquez-Martin,Sílvia Cufí,Bernardo Queralt,Begoña Martin-Castillo,Joan Brunet,Rafael de Llorens,Javier A. Menendez +9 more
TL;DR: Unlike KRAS mutations, which are informative of unresponsiveness to CTX solely in mCRC, hypothesis-generating data suggest that expression status of AR and EPI mRNAs might be evaluated as dynamic predictors of response in KRAS WT patients receiving any CTX-based therapy.
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Val1483Ile in FASN Gene Is Linked to Central Obesity and Insulin Sensitivity in Adult White Men
José María Moreno-Navarrete,Patricia Botas,Sergio Valdés,Francisco J. Ortega,Elías Delgado,Alejandro Vazquez-Martin,Judit Bassols,Gerard Pardo,Wifredo Ricart,Javier A. Menendez,José Manuel Fernández-Real +10 more
TL;DR: Adult white men with the Ile 1483 variant of the FASn gene seem protected from developing central obesity through decreased adipose tissue FASN activity.