J
Javier C. Angulo
Researcher at European University of Madrid
Publications - 436
Citations - 6847
Javier C. Angulo is an academic researcher from European University of Madrid. The author has contributed to research in topics: Cancer & Prostate cancer. The author has an hindex of 36, co-authored 413 publications receiving 5834 citations. Previous affiliations of Javier C. Angulo include University of Alcalá & Wayne State University.
Papers
More filters
Journal ArticleDOI
Oxidative stress and vascular inflammation in aging
TL;DR: Lifestyle attitudes such as caloric restriction and exercise training appear as effective ways to overcome defective antioxidant response and inflammation, favoring successful vascular aging and decreasing the risk for cardiovascular disease.
Journal ArticleDOI
Mechanisms involved in the aging-induced vascular dysfunction.
Mariam El Assar,Javier C. Angulo,Susana Vallejo,Concepción Peiró,Carlos F. Sánchez-Ferrer,Leocadio Rodríguez-Mañas +5 more
TL;DR: Prevention or reversion of those mechanisms leading to endothelial dysfunction through life style modifications or pharmacological interventions could markedly improve cardiovascular health in older people.
Journal ArticleDOI
Mirabegron for the treatment of overactive bladder: a prespecified pooled efficacy analysis and pooled safety analysis of three randomised, double‐blind, placebo‐controlled, phase III studies
Victor W. Nitti,Vikram Khullar,P. Van Kerrebroeck,Sender Herschorn,Javier Cambronero,Javier C. Angulo,Mary Beth Blauwet,Caroline Dorrepaal,Emad Siddiqui,Emad Siddiqui,N. E. Martin +10 more
TL;DR: To examine pooled efficacy data from three, large phase III studies comparing mirabegron (50 and 100 mg) with placebo, and pooled safety data including additional mirabEGron 25 mg and tolterodine extended release (ER) 4 mg results.
Journal Article
High Levels of Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Expression Are Associated with Poor Outcome in Invasive Bladder Cancer
David J. Grignon,Wael Sakr,Marta Toth,Vincent Ravery,Javier C. Angulo,Falah Shamsa,J. Edson Pontes,John C. Crissman,Rafael Fridman +8 more
TL;DR: A potential role for TIMP-2 and BM staining as prognostic indicators in invasive bladder cancer is suggested.
Journal ArticleDOI
Muscularis mucosa differentiates two populations with different prognosis in Stage T1 bladder cancer
Javier C. Angulo,Javier C. Angulo,José I. López,José I. López,David J. Grignon,David J. Grignon,Manuel Sanchez-Chapado,Manuel Sanchez-Chapado +7 more
TL;DR: The present study validates the prognostic significance of such a distinction both by Mantel-Haenszel life table method and Cox's regression analysis and proves the depth of tumor infiltration can be assessed in a considerable proportion of Stage T1 bladder neoplasms.