J
Jean Christophe Ianotto
Publications - 15
Citations - 631
Jean Christophe Ianotto is an academic researcher. The author has contributed to research in topics: Myelofibrosis & Essential thrombocythemia. The author has an hindex of 7, co-authored 15 publications receiving 505 citations.
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Journal ArticleDOI
Myeloproliferative Neoplasm (MPN) Symptom Assessment Form Total Symptom Score: Prospective International Assessment of an Abbreviated Symptom Burden Scoring System Among Patients With MPNs
Robyn M. Emanuel,Amylou C. Dueck,Holly L. Geyer,Jean-Jacques Kiladjian,Stefanie Slot,Sonja Zweegman,Peter A. W. te Boekhorst,Suzan Commandeur,Harry C. Schouten,Federico Sackmann,Ana Kerguelen Fuentes,Dolores Hernández-Maraver,Heike L. Pahl,Martin Griesshammer,Frank Stegelmann,Konstanze Doehner,Thomas Lehmann,Karin Bonatz,Andreas Reiter,Françoise Boyer,Gabriel Etienne,Jean Christophe Ianotto,Dana Ranta,Lydia Roy,Jean-Yves Cahn,Claire N. Harrison,Deepti Radia,Pablo J. Muxi,Norman Maldonado,Carlos Besses,Francisco Cervantes,Peter L. Johansson,Tiziano Barbui,Giovanni Barosi,Alessandro M. Vannucchi,Francesco Passamonti,Bjorn Andreasson,Maria L Ferarri,Alessandro Rambaldi,Jan Samuelsson,Gunnar Birgegård,Ayalew Tefferi,Ruben A. Mesa +42 more
TL;DR: The MPN-SAF TSS is a concise, valid, and accurate assessment of MPN symptom burden with demonstrated clinical utility in the largest prospective MPN symptoms study to date.
Journal ArticleDOI
Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients.
Xenia Cabagnols,Xenia Cabagnols,Fabrizia Favale,Fabrizia Favale,Florence Pasquier,Florence Pasquier,Kahia Messaoudi,Kahia Messaoudi,Jean-Philippe Defour,Jean-Philippe Defour,Jean Christophe Ianotto,Christophe Marzac,Jean Pierre Le Couédic,Jean Pierre Le Couédic,Nathalie Droin,Nathalie Droin,Ilyas Chachoua,Ilyas Chachoua,Rémi Favier,Rémi Favier,M'Boyba Diop,M'Boyba Diop,Valérie Ugo,Nicole Casadevall,Najet Debili,Najet Debili,Hana Raslova,Hana Raslova,Christine Bellanné-Chantelot,Stefan N. Constantinescu,Stefan N. Constantinescu,Olivier Bluteau,Olivier Bluteau,Isabelle Plo,Isabelle Plo,William Vainchenker +35 more
TL;DR: Functional studies on MPLS204P and MPLY591N revealed that they are weak gain-of-function mutants increasing MPL signaling and conferring either TPO hypersensitivity or independence to expressing cells, but with a low efficiency.
Journal ArticleDOI
Symptomatic Profiles of Patients With Polycythemia Vera: Implications of Inadequately Controlled Disease
Holly L. Geyer,Robyn M. Scherber,Heidi E. Kosiorek,Amylou C. Dueck,Jean-Jacques Kiladjian,Zhijian Xiao,Stefanie Slot,Sonja Zweegman,Federico Sackmann,Ana Kerguelen Fuentes,Dolores Hernández-Maraver,Konstanze Döhner,Claire N. Harrison,Deepti Radia,Pablo J. Muxi,Carlos Besses,Francisco Cervantes,Peter L. Johansson,Bjorn Andreasson,Alessandro Rambaldi,Tiziano Barbui,Karin Bonatz,Andreas Reiter,Françoise Boyer,Gabriel Etienne,Jean Christophe Ianotto,Dana Ranta,Lydia Roy,Jean-Yves Cahn,Norman Maldonado,Giovanni Barosi,Maria Luisa Ferrari,Robert Peter Gale,Gunnar Birgegård,Zefeng Xu,Yue Zhang,Xiujuan Sun,Junqing Xu,Peihong Zhang,Peter A. W. te Boekhorst,Suzan Commandeur,Harry C. Schouten,Heike L. Pahl,Martin Griesshammer,Frank Stegelmann,Thomas Lehmann,Zhenya Senyak,Alessandro M. Vannucchi,Francesco Passamonti,Jan Samuelsson,Ruben A. Mesa +50 more
TL;DR: It is suggested that patients with PV who have any one of the features in question (known HU use, known phlebotomy, or splenomegaly) have significant PV-associated symptoms and it demonstrates that many PV symptoms remain severe independent of the number of features present.
Journal ArticleDOI
Associations between gender, disease features and symptom burden in patients with myeloproliferative neoplasms: an analysis by the MPN QOL International Working Group
Holly L. Geyer,Heidi E. Kosiorek,Amylou C. Dueck,Robyn M. Scherber,Stefanie Slot,Sonja Zweegman,Peter A. W. te Boekhorst,Zhenya Senyak,Harry C. Schouten,Federico Sackmann,Ana Kerguelen Fuentes,Dolores Hernández-Maraver,Heike L. Pahl,Martin Griesshammer,Frank Stegelmann,Konstanze Döhner,Thomas Lehmann,Karin Bonatz,Andreas Reiter,Françoise Boyer,Gabriel Etienne,Jean Christophe Ianotto,Dana Ranta,Lydia Roy,Jean-Yves Cahn,Claire N. Harrison,Deepti Radia,Pablo J. Muxi,Norman Maldonado,Carlos Besses,Francisco Cervantes,Peter L. Johansson,Tiziano Barbui,Giovanni Barosi,Alessandro M. Vannucchi,Chiara Paoli,Francesco Passamonti,Bjorn Andreasson,Maria Luisa Ferrari,Alessandro Rambaldi,Jan Samuelsson,Keith Cannon,Gunnar Birgegård,Zhijian Xiao,Zefeng Xu,Yue Zhang,Xiujuan Sun,Junqing Xu,Jean-Jacques Kiladjian,Peihong Zhang,Robert Peter Gale,Ruben A. Mesa +51 more
TL;DR: The role gender plays in the symptomatology of myeloproliferative neoplasms remains under-investigated in this paper, where the authors evaluated how gender relates to patients' characteristics, disease complications and overall symptom expression.
Journal ArticleDOI
Direct oral anticoagulants for myeloproliferative neoplasms: results from an international study on 442 patients.
Tiziano Barbui,Valerio De Stefano,Alessandra Carobbio,Alessandra Iurlo,Alberto Alvarez-Larrán,Beatriz Cuevas,Francisca Ferrer Marin,Alessandro M. Vannucchi,Francesca Palandri,Claire N. Harrison,Hassan Sibai,Martin Griesshammer,Massimiliano Bonifacio,Elena Maria Elli,Chiara Trotti,Steffen Koschmieder,Giuseppe Carli,Giulia Benevolo,Jean Christophe Ianotto,Swati Goel,Anna Falanga,Silvia Betti,Daniele Cattaneo,Eduardo Arellano-Rodrigo,Lara Mannelli,Nicola Vianelli,Andrew J. Doyle,Vikas Gupta,Kai Wille,Douglas Tremblay,John Mascarenhas +30 more