J
Jeffrey L. Lennox
Researcher at Emory University
Publications - 95
Citations - 7717
Jeffrey L. Lennox is an academic researcher from Emory University. The author has contributed to research in topics: Viral load & Raltegravir. The author has an hindex of 42, co-authored 94 publications receiving 7236 citations. Previous affiliations of Jeffrey L. Lennox include Grady Memorial Hospital.
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Journal ArticleDOI
Effect of protein binding on unbound atazanavir and darunavir cerebrospinal fluid concentrations.
Cecile Delille,Sarah T. Pruett,Vincent C. Marconi,Jeffrey L. Lennox,Wendy S. Armstrong,Richard F. Arrendale,Anandi N. Sheth,Kirk A. Easley,Edward P. Acosta,Aswani Vunnava,Ighovwerha Ofotokun +10 more
TL;DR: Low CSF HIV‐1 RNA and neopterin suggest that both regimens resulted in CSF virologic suppression and controlled inflammation.
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The use of HIV-1 integrase inhibitors in antiretroviral naive patients.
TL;DR: Integrase inhibitors provide potent antiretroviral activity, little short-term toxicity and excellent tolerability for patients with preexisting atherosclerosis or cardiac risk factors, and when taken twice daily is as effective and well tolerated as efavirenz.
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Integrated Population Pharmacokinetic/Viral Dynamic Modelling of Lopinavir/Ritonavir in HIV-1 Treatment-Naive Patients
Kun Wang,David Z. D'Argenio,Edward P. Acosta,Anandi N. Sheth,Cecile Delille,Jeffrey L. Lennox,Corenna Kerstner-Wood,Ighovwerha Ofotokun +7 more
TL;DR: The pharmacokinetic–pharmacodynamic model provides a useful tool to quantitatively describe the relationship between LPV/RTV exposure and viral response and could be used as a surrogate assessment of antiretroviral (ARV) activity where adequate early-phase dose-ranging studies are lacking.
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Detection of Infectious Human Immunodeficiency Virus Type 1 in Female Genital Secretions by a Short-Term Culture Method
James E. Cummins,Julie M. Villanueva,Tammy Evans-Strickfaden,Shekou M. Sesay,Sheila R. Abner,Timothy J. Bush,Timothy A. Green,Jeffrey L. Lennox,Tom Wright,Thomas M. Folks,Clyde E. Hart,Charlene S. Dezzutti +11 more
TL;DR: Results indicate that the MAGI assay is more sensitive than PBMC culture methods for detecting infectious virus in female genital secretions, and will improve studies that evaluate sexual transmitted HIV-1.
Journal ArticleDOI
Viral load response to a pneumococcal conjugate vaccine, polysaccharide vaccine or placebo among HIV-infected patients.
Matthew Bidwell Goetz,Daniel R. Feikin,Jeffrey L. Lennox,William A. O'Brien,Cheryl M. Elie,Jay C. Butler,Robert F. Breiman +6 more
TL;DR: The HIV viral load in 66 adults randomly assigned to receive pneumococcal immunization with one or two doses of protein conjugate vaccine, one dose of polysaccharide vaccine, three doses of each, or placebo was determined.