J
Jennifer C. Moore
Researcher at Rutgers University
Publications - 27
Citations - 1366
Jennifer C. Moore is an academic researcher from Rutgers University. The author has contributed to research in topics: Induced pluripotent stem cell & Stem cell. The author has an hindex of 12, co-authored 26 publications receiving 1133 citations.
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Journal ArticleDOI
Multiple knockout mouse models reveal lincRNAs are required for life and brain development
Martin Sauvageau,Martin Sauvageau,Loyal A. Goff,Loyal A. Goff,Loyal A. Goff,Simona Lodato,Simona Lodato,Boyan B. Bonev,Boyan B. Bonev,Abigail F. Groff,Abigail F. Groff,Chiara Gerhardinger,Chiara Gerhardinger,Diana B. Sanchez-Gomez,Ezgi Hacisuleyman,Ezgi Hacisuleyman,Eric Li,Matthew Spence,Stephen C. Liapis,Stephen C. Liapis,William Mallard,William Mallard,Michael A. Morse,Michael A. Morse,Mavis R. Swerdel,Michael F D’Ecclessis,Jennifer C. Moore,Venus Lai,Guochun Gong,George D. Yancopoulos,David Frendewey,Manolis Kellis,Manolis Kellis,Ronald P. Hart,David M. Valenzuela,Paola Arlotta,Paola Arlotta,John L. Rinn,John L. Rinn,John L. Rinn +39 more
TL;DR: It is demonstrated that lncRNAs play critical roles in vivo and provides a framework and impetus for future larger-scale functional investigation into the roles of lncRNA molecules.
Journal ArticleDOI
Ago2 Immunoprecipitation Identifies Predicted MicroRNAs in Human Embryonic Stem Cells and Neural Precursors
Loyal A. Goff,Loyal A. Goff,Jonathan Davila,Mavis R. Swerdel,Jennifer C. Moore,Rick I. Cohen,Hao Wu,Yi E. Sun,Ronald P. Hart +8 more
TL;DR: A large number of new microRNA genes, the majority of which are less conserved than their canonical counterparts, likely represent evolutionarily recent regulators of early differentiation.
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Generation and Transplantation of Reprogrammed Human Neurons in the Brain Using 3D Microtopographic Scaffolds
Aaron L. Carlson,Neal K. Bennett,Nicola L. Francis,Apoorva Halikere,Stephen G. Clarke,Jennifer C. Moore,Ronald P. Hart,Kenneth G Paradiso,Marius Wernig,Joachim Kohn,Zhiping P. Pang,Prabhas V. Moghe +11 more
TL;DR: 3D microscale biomaterials represent a promising platform for the transplantation of therapeutic human neurons with broad neuro-regenerative relevance for cell replacement therapy with human pluripotent stem cell-derived neurons.
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Microfibrous substrate geometry as a critical trigger for organization, self-renewal, and differentiation of human embryonic stem cells within synthetic 3-dimensional microenvironments
Aaron L. Carlson,Charles A. Florek,Joseph J. Kim,Thomas Neubauer,Jennifer C. Moore,Rick I. Cohen,Joachim Kohn,Martin Grumet,Prabhas V. Moghe +8 more
TL;DR: Synthetic substrates with specific 3‐D microgeometries can support hESC colony formation, self‐renewal, and directed differentiation to multiple lineages while obviating the stringent needs for complex, exogenous matrices.
Journal ArticleDOI
Efficient, high-throughput transfection of human embryonic stem cells
Jennifer C. Moore,Kristin Atze,Percy Luk Yeung,Alana J. Toro-Ramos,Cynthia Camarillo,Kevin Thompson,Christopher L. Ricupero,Mark A. Brenneman,Rick I. Cohen,Ronald P. Hart +9 more
TL;DR: This method is effective in the delivery of short synthetic RNA oligonucleotides (siRNA) into hESC for knockdown of translation activity via RNA interference.