R
Ronald P. Hart
Researcher at Rutgers University
Publications - 161
Citations - 8238
Ronald P. Hart is an academic researcher from Rutgers University. The author has contributed to research in topics: Induced pluripotent stem cell & Gene expression. The author has an hindex of 46, co-authored 152 publications receiving 7389 citations. Previous affiliations of Ronald P. Hart include University of Texas Medical Branch & University of Michigan.
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Journal ArticleDOI
Multiple knockout mouse models reveal lincRNAs are required for life and brain development
Martin Sauvageau,Martin Sauvageau,Loyal A. Goff,Loyal A. Goff,Loyal A. Goff,Simona Lodato,Simona Lodato,Boyan B. Bonev,Boyan B. Bonev,Abigail F. Groff,Abigail F. Groff,Chiara Gerhardinger,Chiara Gerhardinger,Diana B. Sanchez-Gomez,Ezgi Hacisuleyman,Ezgi Hacisuleyman,Eric Li,Matthew Spence,Stephen C. Liapis,Stephen C. Liapis,William Mallard,William Mallard,Michael A. Morse,Michael A. Morse,Mavis R. Swerdel,Michael F D’Ecclessis,Jennifer C. Moore,Venus Lai,Guochun Gong,George D. Yancopoulos,David Frendewey,Manolis Kellis,Manolis Kellis,Ronald P. Hart,David M. Valenzuela,Paola Arlotta,Paola Arlotta,John L. Rinn,John L. Rinn,John L. Rinn +39 more
TL;DR: It is demonstrated that lncRNAs play critical roles in vivo and provides a framework and impetus for future larger-scale functional investigation into the roles of lncRNA molecules.
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Type 1 interleukin-1 receptor in the rat brain: distribution, regulation, and relationship to sites of IL-1-induced cellular activation.
TL;DR: The common expression in both species of an IL‐1R in non‐neuronal elements highlights the possibility thatIL‐1‐mediated activation of CRF neurons may result from cytokine‐receptor interaction at vascular, and/or other barrier‐related, sites to trigger release of secondary signalling molecules in a position to interact with components of HPA control circuitry.
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Differential regulation of microRNA stability
Sophie Bail,Mavis R. Swerdel,Hudan Liu,Xinfu Jiao,Loyal A. Goff,Ronald P. Hart,Megerditch Kiledjian +6 more
TL;DR: It is demonstrated that although most miRNA appear to be stable, like mRNAs, miRNAs possess differential stability in human cells and it is found that miR-382, a miRNA that contributes to HIV-1 provirus latency, is unstable in cells.
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Toll‐like receptor (TLR)‐2 and TLR‐4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury
Kristina A. Kigerl,Wenmin Lai,Serge Rivest,Ronald P. Hart,Abhay R. Satoskar,Phillip G. Popovich +5 more
TL;DR: Test whether TLRs are regulated after sterile spinal cord injury (SCI) and their effects on functional and anatomical recovery suggest that in the absence of pathogens, TLR2 and TLR4 are important for coordinating post‐injury sequelae and perhaps in regulating inflammation and gliosis after SCI.
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In Vivo Pharmacokinetics and Regulation of Gene Expression Profiles by Isothiocyanate Sulforaphane in the Rat
Rong Hu,Vidya Hebbar,Bok Ryang Kim,Chi Chen,Bozena Winnik,Brian Buckley,Patricia Soteropoulos,Peter Tolias,Ronald P. Hart,A.-N. Tony Kong +9 more
TL;DR: This in vivo study of Sulforaphane provides the first clue as to the plasma concentrations of SUL, in vivo mitogen-activated protein kinase activations in rat livers, as well as what other genes are modulated in addition to phase II detoxifying genes.