J
Jens Eilers
Researcher at Leipzig University
Publications - 82
Citations - 5918
Jens Eilers is an academic researcher from Leipzig University. The author has contributed to research in topics: Cerebellar cortex & Synaptic plasticity. The author has an hindex of 35, co-authored 76 publications receiving 5433 citations. Previous affiliations of Jens Eilers include Duke University & Max Planck Society.
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Large-scale oscillatory calcium waves in the immature cortex.
TL;DR: A type of large-scale Ca2+ wave that may regulate long-distance wiring in the immature cortex is identified that is associated with field-potential changes and required activation of AMPA and NMDA receptors.
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Importance of the Intracellular Domain of NR2 Subunits for NMDA Receptor Function In Vivo
Rolf Sprengel,Bettina Suchanek,Carla Amico,Rossella Brusa,Nail Burnashev,Andrei Rozov,OØivind Hvalby,Vidar Jensen,Ole Paulsen,Per Andersen,Jeansok J. Kim,Richard F. Thompson,William Sun,Lorna C. Webster,Seth G. N. Grant,Jens Eilers,Arthur Konnerth,Jianying Li,James O. McNamara,Peter H. Seeburg +19 more
TL;DR: It is shown that gene-targeted mice expressing NMDA receptors without the large intracellular C-terminal domain of any one of three NR2 subunits phenotypically resemble mice made deficient in that particular subunit.
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A new class of synaptic response involving calcium release in dendritic spines
TL;DR: The results indicate that these synaptic Ca2+ transients are mediated by activation of metabotropic glutamate-responsive mGluR1-type receptors and require inositol-1,4,5-trisphosphate-mediated Ca1+ release, from intradendritic stores.
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Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene
TL;DR: It is concluded that endogenous calbindin is of crucial importance for integrated nervous system function.
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Subthreshold synaptic Ca2+ signalling in fine dendrites and spines of cerebellar Purkinje neurons.
TL;DR: Clear evidence is reported that non-electrical synaptic integration occurs and that it takes place in restricted dendritic compartments consisting of spines and adjacent fine dendrites in cerebellar Purkinje neurons.