H
Hajime Takechi
Researcher at Fujita Health University
Publications - 84
Citations - 2485
Hajime Takechi is an academic researcher from Fujita Health University. The author has contributed to research in topics: Dementia & Cognition. The author has an hindex of 25, co-authored 73 publications receiving 2238 citations. Previous affiliations of Hajime Takechi include Kyoto Prefectural University of Medicine & Saarland University.
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Journal ArticleDOI
A new class of synaptic response involving calcium release in dendritic spines
TL;DR: The results indicate that these synaptic Ca2+ transients are mediated by activation of metabotropic glutamate-responsive mGluR1-type receptors and require inositol-1,4,5-trisphosphate-mediated Ca1+ release, from intradendritic stores.
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Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids.
Nobuko Hosokawa,Kazunori Hirayoshi,Hitoshi Kudo,Hajime Takechi,Akira Aoike,Keiichi Kawai,Kazuhiro Nagata +6 more
TL;DR: Quercetin interacts with HSF and inhibits the induction of HSPs after heat shock through inhibition of HSF activation, which is regulated by the activation of a heat shock factor (HSF).
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Roles of Glutamate Receptor δ2 Subunit (GluRδ2) and Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Climbing Fiber Synapse Elimination during Postnatal Cerebellar Development
Kouichi Hashimoto,Ryoichi Ichikawa,Hajime Takechi,Yoshiro Inoue,Atsu Aiba,Kenji Sakimura,Masayoshi Mishina,Tsutomu Hashikawa,Arthur Konnerth,Masahiko Watanabe,Masanobu Kano +10 more
TL;DR: These findings suggest that GluRδ2 is required for consolidating PF synapses and restricting CF synapses to the proximal dendrites, whereas the mGluR1-signaling pathway does not affect PF synaptogenesis but is involved in eliminating surplus CFsynapses at the proximate dendrite.
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Cortical Networks Recruited for Time Perception: A Monkey Positron Emission Tomography (PET) Study
Hirotaka Onoe,Masashi Komori,Kayo Onoe,Hajime Takechi,Hajime Takechi,Hideo Tsukada,Yasuyoshi Watanabe,Yasuyoshi Watanabe +7 more
TL;DR: The results indicate that a neural network composed of the posterior inferior parietal cortex to the DLPFC plays a crucial role in the temporal monitoring process in time perception.
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HSP47: a Tissue-Specific, Transformation-Sensitive, Collagen-Binding Heat Shock Protein of Chicken Embryo Fibroblasts.
Kazunori Hirayoshi,Hitoshi Kudo,Hajime Takechi,Akira Nakai,Akihiro Iwamatsu,Kenneth M. Yamada,Kazuhiro Nagata +6 more
TL;DR: Northern (RNA) blot analyses and nuclear run-on assays established that the induction of HSP47 by heat shock and its suppression after transformation of chicken embryo fibroblasts by Rous sarcoma virus are regulated at the transcriptional level.