J
Jérôme Abadie
Researcher at University of Nantes
Publications - 66
Citations - 1657
Jérôme Abadie is an academic researcher from University of Nantes. The author has contributed to research in topics: Cancer & Histiocytic sarcoma. The author has an hindex of 20, co-authored 62 publications receiving 1337 citations. Previous affiliations of Jérôme Abadie include Université Nantes Angers Le Mans & École Normale Supérieure.
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Journal Article
Immunohistochemical detection of proliferating cell nuclear antigen and Ki-67 in mast cell tumors from dogs.
TL;DR: For dogs with solitary cutaneous MCT, determining number of Ki-67-positive nuclei may be useful in predicting prognosis, particularly for dogs with grade-II tumors.
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A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles.
Bruno Pitard,Hélène Pollard,Onnik Agbulut,Olivier Lambert,Jean-Thomas Vilquin,Yan Cherel,Jérôme Abadie,Jane-Lise Samuel,Jean-Louis Rigaud,Séverine Ménoret,Ignacio Anegon,Denis Escande +11 more
TL;DR: PE6400 abolishes the ceiling effect on transgene expression of increasing amounts of naked DNA and permits long-term expression of the beta-galactosidase reporter gene in immunologically tolerant transgenic rats, and provides a simple gene delivery system for skeletal and myocardial gene transfer.
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Naturally occurring melanomas in dogs as models for non-UV pathways of human melanomas.
Marc Gillard,Marc Gillard,Edouard Cadieu,Edouard Cadieu,Clotilde De Brito,Clotilde De Brito,Jérôme Abadie,Béatrice Vergier,Patrick Devauchelle,Frédérique Degorce,Stéphane Dréano,Stéphane Dréano,Aline Primot,Aline Primot,Laetitia Dorso,M. Lagadic,Francis Galibert,Francis Galibert,Benoit Hedan,Benoit Hedan,Marie-Dominique Galibert,Marie-Dominique Galibert,Catherine André,Catherine André +23 more
TL;DR: The relevance of the dog model for comparative oncology of melanomas, especially for the elucidation of non‐UV induced pathways, is supported.
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Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior
B. Hedan,Rachael Thomas,Alison A. Motsinger-Reif,Jérôme Abadie,Catherine André,John M. Cullen,Matthew Breen +6 more
TL;DR: The breed associated clinical features and DNA copy number aberrations exhibited by canine HS offer a valuable model for the human counterpart, providing additional evidence towards elucidation of the pathophysiological and genetic mechanisms associated with histiocytic malignancies.
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Canine invasive mammary carcinomas as models of human breast cancer. Part 1: natural history and prognostic factors
F. Nguyen,Laura Peña,Catherine Ibisch,Delphine Loussouarn,Adelina Gama,Natascha Rieder,Anton Belousov,Mario Campone,Jérôme Abadie +8 more
TL;DR: The short natural history of spontaneous canine invasive mammary carcinomas and high rate of cancer-related death allow for rapid termination of preclinical investigations, highlighting the similarities in cancer biology between both species.