Jerzy Lasota

TL;DR: There may be another gene in the vicinity of the 3p14.2 break of the familial RCC-associated translocation, t(3;8)(p 14.2;q24), which has been hypothesized to affect expression of an RCC suppressor gene or oncogene in the majority of clear cell RCCs.

TL;DR: It becomes even more important for pathologists to familiarize themselves with these protocols and cautions that use of the protocols other than for their intended educational purpose may involve additional considerations that are beyond the scope of these documents.

TL;DR: Results indicate the tumors are true histiocytic lymphomas, which have immunophenotypic features of both ordinary histiocytes and interdigitating reticulum cells.

TL;DR: It is shown that some B-cell lymphomas can have unusual and confusing immunophenotypes, including keratin positivity and leukocyte antigen negativity, and use of PCR-based molecular genetic demonstration of clonal immunoglobulin heavychain gene rearrangement is helpful in establishing the correct diagnosis in such cases.

TL;DR: A panel of rodent-human hybrids carrying portions of 3p, including a hybrid carrying the derivative 8 (der(8)(8pter-->8q24.1::3p14.2-->3pter)) from the RCC family, have been characterized using 3p anchor probes and cytogenetic methods, and a large number of genetically mapped probes were mapped into seven physical intervals between 3p12 and 3pter defined by the hybrid panel.