J
Jes Thorn Clausen
Researcher at Novo Nordisk
Publications - 44
Citations - 3669
Jes Thorn Clausen is an academic researcher from Novo Nordisk. The author has contributed to research in topics: Cocaine and amphetamine regulated transcript & Cart. The author has an hindex of 25, co-authored 44 publications receiving 3559 citations. Previous affiliations of Jes Thorn Clausen include University of Saskatchewan.
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Journal ArticleDOI
Hypothalamic CART is a new anorectic peptide regulated by leptin
Peter Lommer Kristensen,Martin Edward Judge,Lars Thim,Ulla Ribel,Kennet Neist Christjansen,Birgitte Schjellerup Wulff,Jes Thorn Clausen,Per B. Jensen,Ole D. Madsen,Niels Vrang,Philip J. Larsen,Sven Hastrup +11 more
TL;DR: It is shown that CART (cocaine- and amphetamine-regulated transcript), a brain-located peptide, is a satiety factor and is closely associated with the actions of two important regulators of food intake, leptin and neuropeptide Y.
Journal ArticleDOI
Neurochemical characterization of hypothalamic cocaine- amphetamine-regulated transcript neurons.
TL;DR: The present data support a role for CART in neuroendocrine regulation, co-stored with neurotransmitters having both positive (melanin-concentrating hormone) and negative effect on food intake and energy balance.
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Epidermal overexpression of interleukin-19 and -20 mRNA in psoriatic skin disappears after short-term treatment with cyclosporine a or calcipotriol.
Torben Steiniche,Knud Kragballe,John Rømer,Erik Hasselager,Peder Lisby Nørby,Jes Thorn Clausen +5 more
TL;DR: Findings show that IL-19 and IL-20 are synthesized by a distinct population of keratinocytes in skin from psoriatic patients before and during short-term treatment with either oral cyclosporine A or topical calcipotriol.
Journal ArticleDOI
Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: Studies in obese and normal-weight subjects
Ulrick Espelund,Troels Krarup Hansen,Kurt Højlund,Henning Beck-Nielsen,Jes Thorn Clausen,Birgit Sehested Hansen,Hans Ørskov,Jens Otto Lunde Jørgensen,Jan Frystyk +8 more
TL;DR: The hypothesis that food deprivation could impact circadian serum ghrelin levels and unmask meal-independent regulatory mechanisms is tested and there is no evidence that gh Relin stimulates GH release during fasting.
Journal Article
Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting
Csaba Fekete,Emese Mihály,Lu Guang Luo,Joseph Kelly,Jes Thorn Clausen,Quan Fu Mao,William M. Rand,Larry G. Moss,Michael J. Kuhar,Charles H. Emerson,Ivor M. D. Jackson,Ronald M. Lechan +11 more
TL;DR: In this paper, triple-labeling fluorescent in situ hybridization and immunofluorescence were performed to reveal the morphological relationships between pro-TRH mRNA-containing neurons and CART- and alpha-MSH-immunoreactive (IR) axons.