J
Jessica C. Stark
Researcher at Northwestern University
Publications - 30
Citations - 1004
Jessica C. Stark is an academic researcher from Northwestern University. The author has contributed to research in topics: Glycosylation & Biology. The author has an hindex of 11, co-authored 23 publications receiving 630 citations. Previous affiliations of Jessica C. Stark include Stanford University & Cornell University.
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Journal ArticleDOI
Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.
Thapakorn Jaroentomeechai,Jessica C. Stark,Aravind Natarajan,Cameron J. Glasscock,Laura E. Yates,Karen J. Hsu,Milan Mrksich,Michael C. Jewett,Matthew P. DeLisa +8 more
TL;DR: A novel cell-free glycoprotein synthesis (CFGpS) technology that seamlessly integrates protein biosynthesis with asparagine-linked protein glycosylation will facilitate fundamental understanding in glycoscience and make possible applications in on demand biomanufacturing of glycoproteins.
Journal ArticleDOI
Cell-Free Synthetic Biology: Engineering Beyond the Cell
TL;DR: Given the flexibility of cell-free systems, CFPS holds promise to be a powerful tool for synthetic biology as well as a protein production technology in years to come.
Journal ArticleDOI
BioBits™ Explorer: A modular synthetic biology education kit.
Ally Huang,Ally Huang,Peter Q. Nguyen,Peter Q. Nguyen,Jessica C. Stark,Melissa K. Takahashi,Nina M. Donghia,Tom Ferrante,Aaron J. Dy,Karen J. Hsu,Rachel S. Dubner,Keith Pardee,Michael C. Jewett,James J. Collins +13 more
TL;DR: The BioBits™ Explorer kit enables hands-on demonstrations of cutting-edge science that are inexpensive and easy to use, circumventing many current barriers for implementing exploratory biology experiments in classrooms.
Journal ArticleDOI
BioBits™ Bright: A fluorescent synthetic biology education kit.
Jessica C. Stark,Ally Huang,Ally Huang,Peter Q. Nguyen,Peter Q. Nguyen,Rachel S. Dubner,Karen J. Hsu,Thomas C. Ferrante,Mary Anderson,Ada Kanapskyte,Quinn Mucha,Jessica S. Packett,Palak Patel,Richa Patel,Deema Qaq,Tyler Zondor,Julie Burke,Thomas Martinez,Ashlee Miller-Berry,Aparna Puppala,Kara Reichert,Miriam Schmid,Lance Brand,Lander R. Hill,Jemima F. Chellaswamy,Nuhie Faheem,Suzanne Fetherling,Elissa Gong,Eddie Marie Gonzalzles,Teresa Granito,Jenna Koritsaris,Binh Nguyen,Sujud Ottman,Christina Palffy,Angela Patel,Sheila Skweres,Adriane Slaton,Ta Rhonda Woods,Nina M. Donghia,Keith Pardee,James J. Collins,Michael C. Jewett +41 more
TL;DR: BioBits™ Bright is presented, a shelf-stable, just-add-water synthetic biology education kit with easy visual outputs enabled by expression of fluorescent proteins in freeze-dried, cell-free reactions that promise to enhance biology education both inside and outside the classroom.
Journal ArticleDOI
A cell-free biosynthesis platform for modular construction of protein glycosylation pathways
Weston Kightlinger,Katherine E. Duncker,Ashvita Ramesh,Ariel H. Thames,Aravind Natarajan,Jessica C. Stark,Allen Yang,Liang Lin,Milan Mrksich,Matthew P. DeLisa,Michael C. Jewett +10 more
TL;DR: A modular, versatile cell-free platform for glycosylation pathway assembly by rapid in vitro mixing and expression (GlycoPRIME), to evaluate 37 putative glyCosylation pathways and discover routes to 18 new glycoprotein structures.