J
Jessie E. King
Researcher at Massachusetts Institute of Technology
Publications - 2
Citations - 3536
Jessie E. King is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: P70-S6 Kinase 1 & mTORC2. The author has an hindex of 2, co-authored 2 publications receiving 3325 citations.
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Journal ArticleDOI
mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
Do Hyung Kim,Dos D. Sarbassov,Siraj M. Ali,Jessie E. King,Robert R. Latek,Hediye Erdjument-Bromage,Paul Tempst,David M. Sabatini +7 more
TL;DR: It is reported that mTOR forms a stoichiometric complex with raptor, an evolutionarily conserved protein with at least two roles in the mTOR pathway that through its association with mTOR regulates cell size in response to nutrient levels.
Journal ArticleDOI
Enumeration of the Simian Virus 40 Early Region Elements Necessary for Human Cell Transformation
William C. Hahn,Scott K. Dessain,Scott K. Dessain,Mary W. Brooks,Jessie E. King,Brian Elenbaas,David M. Sabatini,James A. DeCaprio,Robert A. Weinberg +8 more
TL;DR: Observations define the elements of the SV40 ER required for the transformation of human cells and begin to delineate a set of intracellular pathways whose disruption, in aggregate, appears to be necessary to generate tumorigenic human cells.