J
Ji Ping Wang
Researcher at Northwestern University
Publications - 55
Citations - 4059
Ji Ping Wang is an academic researcher from Northwestern University. The author has contributed to research in topics: Nucleosome & Histone. The author has an hindex of 24, co-authored 54 publications receiving 3644 citations. Previous affiliations of Ji Ping Wang include La Jolla Institute for Allergy and Immunology.
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Journal ArticleDOI
A genomic code for nucleosome positioning
Eran Segal,Yvonne N. Fondufe-Mittendorf,Lingyi Chen,Annchristine Thåström,Yair Field,Irene K. Moore,Ji Ping Wang,Jonathan Widom +7 more
TL;DR: This work isolated nucleosome-bound sequences at high resolution from yeast and used these sequences in a new computational approach to construct and validate experimentally a nucleosom–DNA interaction model, and to predict the genome-wide organization of nucleosomes.
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A map of nucleosome positions in yeast at base-pair resolution
TL;DR: The resulting map locates nucleosomes positions genome-wide in unprecedented detail and accuracy and shows new aspects of the in vivo nucleosome organization that are linked to transcription factor binding, RNA polymerase pausing and the higher-order structure of the chromatin fibre.
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Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation
Relja Popovic,Eva Martinez-Garcia,Eugenia G. Giannopoulou,Quanwei Zhang,Qingyang Zhang,Teresa Ezponda,Mrinal Y. Shah,Yupeng Zheng,Christine Will,Eliza C. Small,Youjia Hua,Marinka Bulic,Yanwen Jiang,Matteo Carrara,Raffaele A. Calogero,William L. Kath,Neil L. Kelleher,Ji Ping Wang,Olivier Elemento,Jonathan D. Licht +19 more
TL;DR: This work elucidates previously unrecognized interplay between M MSET and EZH2 in myeloma oncogenesis and identifies domains to be considered when designing inhibitors of MMSET function.
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Insights into Nucleosome Organization in Mouse Embryonic Stem Cells through Chemical Mapping
TL;DR: An accurate method for defining the nucleosome landscape is established and it is shown that nucleosomes occupy DNA targets for a subset of DNA-binding proteins, including CCCTC-binding factor (CTCF) and pluripotency factors.
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Predicting nucleosome positioning using a duration Hidden Markov Model.
TL;DR: Simulation studies show that modeling the linker length distribution and utilizing a base composition re-scaling method both improve the prediction of nucleosome positioning regarding sensitivity and false discovery rate.