Ji Yeun Lee

TL;DR: The results suggest that a highly diverse repertoire is maintained despite thymic involution; however, peripheral fitness selection of T cells leads to repertoire perturbations that can influence the immune response in the elderly.

TL;DR: Most peanut allergen-binding B cells isolated by means of antigen-specific flow sorting express mutated and isotype-switched antibodies, and the results suggest that oral immunotherapy can stimulate somatic mutation of allerGEN-specific IgG4.

TL;DR: In this article , the authors analyzed healthy subjects receiving two doses of the Pfizer/BioNTech BNT162b2 vaccine and found that vaccination resulted in robust spike-specific T cell responses for the dominant CD4+ and CD8+ epitopes.

TL;DR: In this article , the authors analyzed healthy subjects receiving two doses of the Pfizer/BioNTech BNT162b2 vaccine and found that vaccination resulted in robust spike-specific T cell responses for the dominant CD4+ and CD8+ epitopes.

TL;DR: In this article , the authors describe viral RNA shedding duration in hospitalized patients and identify patients with recurrent shedding and show correlates of adaptive immunity at reinfection, including a differential response in neutralizing antibodies to a D614G pseudovirus.