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William R. Berrington
Researcher at University of Washington
Publications - 27
Citations - 2478
William R. Berrington is an academic researcher from University of Washington. The author has contributed to research in topics: Immune system & Legionella pneumophila. The author has an hindex of 16, co-authored 25 publications receiving 1865 citations. Previous affiliations of William R. Berrington include Emory University.
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Journal ArticleDOI
Multiple early factors anticipate post-acute COVID-19 sequelae
Yapeng Su,Dan Yuan,Daniel G. Chen,Rachel Ng,Kai Wang,Jongchan Choi,Sarah Li,Sunga Hong,Rongyu Zhang,Jingyi Xie,Sergey A. Kornilov,Kelsey Scherler,A.-J. Pavlovitch-Bedzyk,Shen Dong,Christopher Lausted,Inyoul Lee,Shannon Fallen,Chengzhen L. Dai,Priyanka Baloni,Brett Smith,Venkata R. Duvvuri,Kristin G. Anderson,Jing Wei Li,Fan Yang,Caroline J. Duncombe,Denise J. McCulloch,Clifford Rostomily,Pamela Troisch,Jing Zhou,Sean Mackay,Quinn DeGottardi,Damon May,Ruth T. Taniguchi,Rachel M. Gittelman,Mark Klinger,Thomas M. Snyder,Ryan Roper,Gladys Wojciechowska,Kim Murray,Rick Edmark,Simon Evans,Lesley Jones,Yon-gan Zhou,Lee Rowen,Rachel Xia-Ying Liu,William Chour,Heather Algren,William R. Berrington,Julie A. Wallick,Rebecca Cochran,Mary Micikas,Christos J. Petropoulos,Hunter Cole,Trevan D Fischer,Wei Wei,Dave S.B. Hoon,Nathan D. Price,Naeha Subramanian,Joshua A. Hill,Jenn J. Hadlock,Andrew T. Magis,Antoni Ribas,Lewis L. Lanier,Scott D. Boyd,Jeffrey A. Bluestone,Helen Y. Chu,Leroy Hood,Raphael Gottardo,Philip D. Greenberg,Mark M. Davis,Jason D Goldman,James R. Heath +71 more
TL;DR: Huang et al. as discussed by the authors performed a deep multi-omic, longitudinal investigation of 309 COVID-19 patients from initial diagnosis to convalescence (2-3 months later), integrated with clinical data and patient-reported symptoms.
Journal ArticleDOI
Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits
C R White,Victor M. Darley-Usmar,William R. Berrington,Michelle McAdams,J Z Gore,J A Thompson,Dale A. Parks,Margaret M. Tarpey,Bruce A. Freeman +8 more
TL;DR: It is hypothesized that increases in plasma cholesterol induce the release of XO into the circulation, where it binds to endothelial cell glycosaminoglycans and impairs endothelium-dependent vascular responses.
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Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug.
Thomas Münzel,S Kurz,Sanjay Rajagopalan,M Thoenes,William R. Berrington,J A Thompson,Bruce A. Freeman,David G. Harrison +7 more
TL;DR: The ability of hydralazine to inhibit vascular .O2- anion production represents a novel mechanism of action for this drug.
Journal ArticleDOI
Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs.
Peter Jorth,Benjamin J. Staudinger,Xia Wu,Katherine B. Hisert,Hillary S. Hayden,Jayanthi Garudathri,Christopher L. Harding,Matthew C. Radey,Amir Rezayat,Gilbert E. Bautista,William R. Berrington,Amanda F. Goddard,Chunxiang Zheng,Angus Angermeyer,Mitchell J. Brittnacher,Jacob O. Kitzman,Jay Shendure,Corinne L. Fligner,John E. Mittler,Moira L. Aitken,Colin Manoil,James E. Bruce,Timothy L. Yahr,Pradeep K. Singh +23 more
TL;DR: It is suggested that bacterial intermixing is limited in CF lungs and that regional selective pressures may markedly differ, which may explain how specialized bacterial variants arise during infection and raise the possibility that pathogen diversification occurs in other chronic infections characterized by spatially heterogeneous conditions.
Journal ArticleDOI
Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?
TL;DR: Recent discoveries in human genetic studies are emphasized and correlated with efforts to understand how these variants alter the molecular and cellular functions that regulate the macrophage response to MTb.