S
Scott D. Boyd
Researcher at Stanford University
Publications - 167
Citations - 13015
Scott D. Boyd is an academic researcher from Stanford University. The author has contributed to research in topics: Antibody & Medicine. The author has an hindex of 42, co-authored 129 publications receiving 9050 citations. Previous affiliations of Scott D. Boyd include Boston Children's Hospital & Massachusetts Institute of Technology.
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Journal ArticleDOI
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
Hua-Xin Liao,Rebecca M. Lynch,Tongqing Zhou,Feng Gao,Feng Gao,S. Munir Alam,S. Munir Alam,Scott D. Boyd,Andrew Fire,Krishna M. Roskin,Chaim A. Schramm,Zhenhai Zhang,Jiang Zhu,Lawrence Shapiro,Lawrence Shapiro,Nisc Comparative Sequencing Program,James C. Mullikin,Sandrasegaram Gnanakaran,Peter T. Hraber,Kevin Wiehe,Kevin Wiehe,Garnett Kelsoe,Garnett Kelsoe,Guang Yang,Guang Yang,Shi-Mao Xia,Shi-Mao Xia,David C. Montefiori,David C. Montefiori,Robert Parks,Robert Parks,Krissey E. Lloyd,Krissey E. Lloyd,Richard M. Scearce,Richard M. Scearce,Kelly A. Soderberg,Kelly A. Soderberg,Myron S. Cohen,Gift Kamanga,Mark K. Louder,Lillian Tran,Yue Chen,Yue Chen,Fangping Cai,Fangping Cai,Sheri Chen,Sheri Chen,Stephanie Moquin,Xiulian Du,M. Gordon Joyce,Sanjay Srivatsan,Baoshan Zhang,Anqi Zheng,George M. Shaw,Beatrice H. Hahn,Thomas B. Kepler,Bette T. Korber,Peter D. Kwong,John R. Mascola,Barton F. Haynes,Barton F. Haynes +60 more
TL;DR: The isolation, evolution and structure of a broadly neutralizing antibody from an African donor followed from the time of infection and its co-crystal structure revealed a new loop-based mechanism of CD4-binding-site recognition.
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Identifying specificity groups in the T cell receptor repertoire
Jacob Glanville,Huang Huang,Allison Nau,Olivia Hatton,Lisa E. Wagar,Florian Rubelt,Xuhuai Ji,Arnold Han,Sheri M. Krams,Christina Pettus,Nikhil Haas,Cecilia S. Lindestam Arlehamn,Alessandro Sette,Scott D. Boyd,Thomas J. Scriba,Olivia M. Martinez,Mark M. Davis +16 more
TL;DR: The GLIPH algorithm can analyse large numbers of TCR sequences and define TCR specificity groups shared by TCRs and individuals, which should greatly accelerate the analysis of T cell responses and expedite the identification of specific ligands.
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Determinants of nucleosome organization in primary human cells
TL;DR: This work uses deep sequencing to map nucleosome positions in three primary human cell types and in vitro and unveils an interplay of sequence-based nucleosomal preferences and non-nucleosomal factors in determining nucleosomes organization within mammalian cells.
Journal ArticleDOI
Diversity and clonal selection in the human T-cell repertoire.
Qian Qi,Yi Liu,Yong Cheng,Jacob Glanville,David W. Zhang,Ji Yeun Lee,Richard A. Olshen,Cornelia M. Weyand,Scott D. Boyd,Jörg J. Goronzy +9 more
TL;DR: The results suggest that a highly diverse repertoire is maintained despite thymic involution; however, peripheral fitness selection of T cells leads to repertoire perturbations that can influence the immune response in the elderly.
Journal ArticleDOI
B7-1 and B7-2 Have Overlapping, Critical Roles in Immunoglobulin Class Switching and Germinal Center Formation
Frank Borriello,Michael P. Sethna,Scott D. Boyd,A. Nicola Schweitzer,Elizabeth A. Tivol,Douglas Jacoby,Terry B. Strom,Elizabeth M. Simpson,Gordon J. Freeman,Arlene H. Sharpe +9 more
TL;DR: The results demonstrate that B7-mediated signaling plays a critical role in germinal center formation and immunoglobulin class switching in vivo and that the induction of B 7-1 by adjuvant in B8-2-deficient mice can compensate for the absence of B7,2.