Jie Niu

TL;DR: The synthesis of antimicrobial peptide conjugated cationic AuNPs (AuNPs@PEP) as highly efficient carriers for gene delivery to stem cells with antibacterial ability is reported, suggesting its potential as a multifunctional system with both gene delivery and antibacterial abilities in clinic.

TL;DR: The synthesis of the TAT peptide conjugated cationic noble metal nanoparticles (metal NPs@PEI-TAT) are reported as highly efficient carriers for gene delivery to stem cells and enhance their directed differentiation for biomedical application.

TL;DR: Evidence is provided that penetrating peptide conjugated cationic gold nanoparticle offers a promising vehicle for both the skin penetration and transfection of pDNAs, possessing great potential in topical gene therapy.

TL;DR: I-P-OMVs are the first nanoplatforms to induce transdermal photo-TRAIL–programmed therapy in melanoma with enhanced antitumor performance and high safety, having great potential in cancer therapy.

TL;DR: This study provides a proof-of-concept design of pH-switchable cationic micelles as transdermal gene delivery nanoplatforms with targeting effect for melanoma therapy, which may be adapted widely in the treatment of various superficial tumors and skin genetic diseases.