Jin Wang

TL;DR: Using a large computed Tomography database from 4,154 patients, an AI system is developed that can diagnose NCP and differentiate it from other common pneumonia and normal controls and is made available globally to assist the clinicians to combat COVID-19.

TL;DR: Biepitopic CAR T against BCMA represents a promising therapy for R/R MM, while most adverse effects are clinically manageable, and CAR T treatment can eventually be combined with other effective therapeutics to treat newly diagnosed MM.

TL;DR: Adult patients with B- cell acute lymphoblastic leukemia had more cooperative mutations and greater enrichment for alterations of epigenetic modifiers and genes linked to B-cell development, suggesting difference in the target cells of transformation between adult and pediatric patients and may explain in part the disparity in their responses to treatment.

TL;DR: The role of lysine acetylation in the cytoplasm driving and coordinating key events such as cytoskeleton dynamics, intracellular trafficking, vesicle fusion, metabolism, and stress response is demonstrated.

TL;DR: Together, these results identify IRX1 as a prometastatic gene, implicate IRX 1 hypomethylation as a potential molecular marker for lung metastasis, and suggest that epigenetic reversion ofIRX1 activation may be beneficial for controlling osteosarcoma metastasis.