J
Jinghua Yu
Researcher at Geron Corporation
Publications - 2
Citations - 2369
Jinghua Yu is an academic researcher from Geron Corporation. The author has contributed to research in topics: Enhancer & Position effect. The author has an hindex of 2, co-authored 2 publications receiving 2319 citations.
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Journal ArticleDOI
The RNA component of human telomerase
Junli Feng,Walter Funk,Sy Shi Wang,Scott L. Weinrich,Ariel A. Avilion,Choy-Pik Chiu,Robert Adams,Edwin Chang,Richard C. Allsopp,Jinghua Yu,Siyuan Le,Michael D. West,Calvin B. Harley,William H. Andrews,Carol W. Greider,Bryant Villeponteau +15 more
TL;DR: Human cell lines that expressed hTR mutated in the template region generated the predicted mutant telomerase activity, and cells transfected with an antisense hTR lost telomeric DNA and began to die after 23 to 26 doublings.
Journal ArticleDOI
A 5′ β-globin matrix-attachment region and the polyoma enhancer together confer position-independent transcription
TL;DR: The results suggest that the beta Glb-MAR may work synergistically with particular enhancer elements to dampen chromosomal position effects and ensure high-level expression.