J
João C. Setubal
Researcher at University of São Paulo
Publications - 216
Citations - 13903
João C. Setubal is an academic researcher from University of São Paulo. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 50, co-authored 195 publications receiving 12114 citations. Previous affiliations of João C. Setubal include Virginia Bioinformatics Institute & University of Washington.
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Book ChapterDOI
Towards a Hybrid Federated Cloud Platform to Efficiently Execute Bioinformatics Workflows
Hugo Saldanha,Edward Ribeiro,Carlos Borges,Aleteia P. F. Araujo,Ricardo Gallon,Maristela Holanda,Maria Emilia M. T. Walter,Roberto C. Togawa,João C. Setubal +8 more
TL;DR: Current generation of high-throughput DNA sequencing machines can generate large amounts of DNA sequence data, and the Human Microbiome project and the 1000 Genomes project are two examples of projects that are generating terabyte-scale amounts ofDNA sequence.
Journal ArticleDOI
Proteomics-based identification of differentially abundant proteins reveals adaptation mechanisms of Xanthomonas citri subsp. citri during Citrus sinensis infection.
Leandro Marcio Moreira,Márcia Regina Soares,Agda Paula Facincani,Cristiano Barbalho Ferreira,Rafael Marini Ferreira,Maria Inês Tiraboschi Ferro,Fabio C. Gozzo,Érica Barbosa Felestrino,Renata de Almeida Barbosa Assis,Camila Carrião Machado Garcia,João C. Setubal,João C. Setubal,Jesus Aparecido Ferro,Julio Cezar Franco de Oliveira +13 more
TL;DR: This is the first time that a protein repertoire is shown to be active and working in an integrated manner during the infection process in a compatible host, pointing to an elaborate mechanism for adaptation of Xac once inside the plant.
Journal ArticleDOI
Analysis of expressed sequence tags from the agarophyte Gracilaria tenuistipitata (Rhodophyta)
Pi Nyvall Collén,Pi Nyvall Collén,Jonas Collén,Marcelo S. Reis,Marianne Pedersén,João C. Setubal,Alessandro M. Varani,Pio Colepicolo,Mariana Cabral de Oliveira +8 more
TL;DR: The largest functional group was genes involved in metabolism with 14% of the ESTs; other large functional categories included energy, transcription, and protein synthesis and destination, and the codon bias was found to be limited with all codon combinations used.
Journal ArticleDOI
Comparative Analysis of Ralstonia solanacearum Methylomes.
Ivan Erill,Ivan Erill,Marina Puigvert,Marina Puigvert,Ludovic Legrand,Rodrigo Guarischi-Sousa,Céline Vandecasteele,João C. Setubal,Stéphane Genin,Alice Guidot,Marc Valls,Marc Valls +11 more
TL;DR: Analysis of genome-wide modification patterns identified a significant correlation between DNA modification and transposase genes in R. solanacearum UY031, driven by the presence of a high copy number of ISrso3 insertion sequences in this genome and pointing to a novel mechanism for regulation of transposition.
Journal Article
A framework based on Web service orchestration for bioinformatics workflow management
TL;DR: A framework to improve interoperability at the syntactic and semantic levels, and the use of scientific workflows to coordinate services to be executed, including their interdependencies and service orchestration is implemented.