J
Johan P. Turkenburg
Researcher at University of York
Publications - 126
Citations - 8279
Johan P. Turkenburg is an academic researcher from University of York. The author has contributed to research in topics: Hydrolase & Glycoside hydrolase. The author has an hindex of 41, co-authored 124 publications receiving 7492 citations. Previous affiliations of Johan P. Turkenburg include New York University & Newcastle University.
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Snapshots of the Catalytic Cycle of the Industrial Enzyme α-Amino-ε-Caprolactam Racemase (ACLR) Observed Using X-ray Crystallography
TL;DR: High-resolution structures of wild-type and variant ACLRs from Rhizobium freirei are reported, substantiate suggestions of a two-base mechanism, in which the PLP-binding K267 and D210 serve as proton donors in the racemization.
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The efficiency of insulin production and its content in insulin-expressing model β-cells correlate with their Zn2+ levels
Petra Dzianová,Seiya Asai,Seiya Asai,Martina Chrudinová,Lucie Kosinová,Pavlo Potalitsyn,Pavlo Potalitsyn,Pavel Šácha,Romana Hadravová,Irena Selicharová,Jan Kříž,Johan P. Turkenburg,Andrzej M. Brzozowski,Jiří Jiráček,Lenka Žáková +14 more
TL;DR: It was showed that the disruption of zinc homeostasis in the model β-cells correlated with their impaired insulin and ZnT8 production, indicating a need for in-depth fundamental research about the role of zinc in insulin production and storage.
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Cellovibrio Cellulosa Alpha-L-Arabinanase 43A Has a Novel Five-Blade Beta-Propeller Fold
Didier Nurizzo,Johan P. Turkenburg,Simon J. Charnock,Shirley M. Roberts,Eleanor J. Dodson,Vincent A. McKie,Edward J. Taylor,Harry J. Gilbert,Gideon J. Davies +8 more
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Structure of a Cys25->Ser Mutant of Human Cathepsin Cathepsin S
Johan P. Turkenburg,Marieke B.A.C. Lamers,Andrzej M. Brzozowski,Lisa Wright,Roderick E. Hubbard,S.L Sturt,David Williams +6 more
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Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: a powerful quality-control tool.
Christian Grundahl Frankær,Olga V. Moroz,Johan P. Turkenburg,Stein Ivar Aspmo,Majbritt Thymark,Esben Peter Friis,Kenny Ståhl,Jens Erik Nielsen,Keith S. Wilson,Pernille Harris +9 more
TL;DR: It is proposed that XRPD provides an excellent quality-control tool for such suspensions and there are at least three polymorphs present in the production suspension, albeit with the 1ndq-like microcrystals predominating.