J
Johan P. Turkenburg
Researcher at University of York
Publications - 126
Citations - 8279
Johan P. Turkenburg is an academic researcher from University of York. The author has contributed to research in topics: Hydrolase & Glycoside hydrolase. The author has an hindex of 41, co-authored 124 publications receiving 7492 citations. Previous affiliations of Johan P. Turkenburg include New York University & Newcastle University.
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Journal ArticleDOI
Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. family GH3 β-D-glucosidases.
Jon Agirre,Antonio Ariza,Wendy A. Offen,Johan P. Turkenburg,Shirley M. Roberts,Stuart McNicholas,Paul Harris,Brett Mcbrayer,Jan Dohnalek,Kevin Cowtan,Gideon J. Davies,Keith S. Wilson +11 more
TL;DR: The three-dimensional structures of two industrially important family GH3 β-d-glucosidases from A. fumigatus and A. oryzae are reported at 1.95 Å resolution, and both enzymes show extensive N-glycosylation.
Journal ArticleDOI
Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface
Emília Antolíková,Lenka Žáková,Johan P. Turkenburg,Christopher J. Watson,Ivona Hančlová,Miloslav Sanda,Alan Cooper,Tomáš Kraus,A. Marek Brzozowski,Jiří Jiráček +9 more
TL;DR: All examined analogues crystallized only in the most stable R6 form of insulin oligomers (even if the dimer interface was totally disrupted), confirming the role of R6-specific intra/intermolecular interactions for hexamer stability.
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Insights into the structural determinants of cohesin-dockerin specificity revealed by the crystal structure of the type II cohesin from Clostridium thermocellum SdbA.
Ana Luísa Carvalho,Virgínia M. R. Pires,Tracey M. Gloster,Johan P. Turkenburg,José A. M. Prates,Luís M. A. Ferreira,Maria João Romão,Gideon J. Davies,Carlos M. G. A. Fontes,Harry J. Gilbert +9 more
TL;DR: The crystal structure of the Type II cohesin (CohII) is reported from the Clostridium thermocellum cell surface anchoring protein SdbA, which is very similar to Type I cohesins, and the dockerin binding site is likely to be conserved in the two proteins.
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Structural and functional analysis of the tandem β-zipper interaction of a streptococcal protein with human fibronectin
Nicole C. Norris,Richard J. Bingham,Gemma Harris,Adrian Speakman,Richard P.O. Jones,Andrew P. Leech,Johan P. Turkenburg,Jennifer R. Potts +7 more
TL;DR: It is proposed that in SfbI-5, the binding energy for the tandem β-zipper interaction with Fn is distributed across the interface rather than concentrated in a small number of “hot spot” residues that are frequently observed in the interactions of folded proteins.
Journal ArticleDOI
Thermodynamic and structural investigation of the specific SDS binding of humicola insolens cutinase
David Kold,Zbigniew Dauter,Anne Kjær Laustsen,Andrzej M. Brzozowski,Johan P. Turkenburg,Anders Dybdal Nielsen,Heidi Koldsø,Evamaria I. Petersen,Birgit Schiøtt,Leonardo De Maria,Keith S. Wilson,Allan Svendsen,Reinhard Wimmer +12 more
TL;DR: The interaction of cutinase from the thermophilic fungus Humicola insolens with the anionic surfactant SDS is reported, and the enzyme specifically binds a single SDS molecule under nondenaturing concentrations.