J
John D. Cahoy
Researcher at Stanford University
Publications - 4
Citations - 4089
John D. Cahoy is an academic researcher from Stanford University. The author has contributed to research in topics: Transcriptome & Oligodendrocyte. The author has an hindex of 4, co-authored 4 publications receiving 3624 citations.
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Journal ArticleDOI
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function.
John D. Cahoy,Ben Emery,Amit Kaushal,Lynette C. Foo,Jennifer L. Zamanian,Karen S. Christopherson,Yi Xing,Jane L. Lubischer,Paul A. Krieg,Sergey A. Krupenko,Wesley J. Thompson,Ben A. Barres +11 more
TL;DR: These findings call into question the concept of a “glial” cell class as the gene profiles of astrocyte and oligodendrocytes are as dissimilar to each other as they are to neurons, for better understanding of neural development, function, and disease.
Journal ArticleDOI
The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells
TL;DR: This analysis has identified that RXRalpha signaling cascade is specifically enriched at the BBB, implicating this pathway in regulating this vital barrier and providing a resource for understanding CNS endothelial cells and their interaction with neural and hematogenous cells.
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Myelin Gene Regulatory Factor Is a Critical Transcriptional Regulator Required for CNS Myelination
Ben Emery,Dritan Agalliu,John D. Cahoy,Trent A. Watkins,Jason C. Dugas,Sara B. Mulinyawe,Adilijan Ibrahim,Keith L. Ligon,David H. Rowitch,Ben A. Barres +9 more
TL;DR: Gen model 98, which is named myelin gene regulatory factor (MRF), is established as a transcriptional regulator required for CNS myelination and oligodendrocyte maturation and CNSMyelination.
Journal ArticleDOI
Development of a method for the purification and culture of rodent astrocytes
Lynette C. Foo,Nicola J. Allen,Eric A. Bushong,P. Britten Ventura,Won-Suk Chung,Lu Zhou,John D. Cahoy,Richard Daneman,Hui Zong,Mark H. Ellisman,Ben A. Barres +10 more
TL;DR: It is found that some developing astrocytes normally undergo apoptosis in vivo and that the vast majority of astroCytes contact blood vessels, suggesting that astrocyts are matched to blood vessels by competing for vascular-derived trophic factors such as HBEGF.