J
John Douglas Mcpherson
Researcher at University of California, Davis
Publications - 216
Citations - 73141
John Douglas Mcpherson is an academic researcher from University of California, Davis. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 74, co-authored 199 publications receiving 67145 citations. Previous affiliations of John Douglas Mcpherson include National University of Singapore & Case Western Reserve University.
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Journal ArticleDOI
Molecular cytogenetic delineation of the critical deleted region in the 5q- syndrome.
Rina J. Jaju,Jacqueline Boultwood,Fiona J. Oliver,Markus Kostrzewa,Carrie Fidler,Norman E. Parker,John Douglas Mcpherson,Stephan W. Morris,Ulrich Müller,James S. Wainscoat,Lyndal Kearney +10 more
TL;DR: FISH analysis of two patients with 5q− syndrome and small deletions resulted in the narrowing of the common deleted region within 5q31 to approximately 3 Mb, flanked by the adrenergic receptor β2 (ADRB2) and IL12B genes.
Journal Article
Association between Ag1-CA alleles and severity of autosomal recessive proximal spinal muscular atrophy.
Christine J. DiDonato,Kenneth Morgan,John D. Carpten,Paul A. Fuerst,Susan E. Ingraham,Gary Prescott,John Douglas Mcpherson,Brunhilde Wirth,Klaus Zerres,Orest Hurko,John J. Wasmuth,Jerry R. Mendell,Arthur H.M. Burghes,Louise R. Simard +13 more
TL;DR: The results indicate that Ag1-CA is the most closely linked marker to SMA and defines the critical candidate-gene region, and a model that should be taken into consideration when screening candidate SMA genes is proposed.
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Genomic Support for a Moa–Tinamou Clade and Adaptive Morphological Convergence in Flightless Ratites
TL;DR: Analysis of morphological characters reinterpreted on a 27-gene paleognath topology indicates that many characters are convergent in the ratites, probably as the result of adaptation to a cursorial life style.
Journal ArticleDOI
Regulation of protein synthesis: translational control by procollagen-derived fragments
TL;DR: It is shown that the intact peptide acts on procollagen mRNA translation by inhibition of polypeptide chain elongation or termination, or both, whereas the nonspecific inhibitory activity of the unfolded peptide and its derivatives can be attributed to an inhibition of chain initiation.
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Evidence that multiple genetic variants of MC4R play a functional role in the regulation of energy expenditure and appetite in Hispanic children
Shelley A. Cole,Nancy F. Butte,V. Saroja Voruganti,Guowen Cai,Karin Haack,Jack W. Kent,John Blangero,Anthony G. Comuzzie,John Douglas Mcpherson,Richard A. Gibbs +9 more
TL;DR: This comprehensive investigation provides strong evidence that MC4R genetic variants are likely to play a functional role in the regulation of weight, not only through energy intake but through energy expenditure.