J
John F. Burke
Researcher at University of California, San Francisco
Publications - 148
Citations - 5704
John F. Burke is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 37, co-authored 122 publications receiving 4482 citations. Previous affiliations of John F. Burke include University of San Francisco & Uniformed Services University of the Health Sciences.
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Journal ArticleDOI
Direct recordings of grid-like neuronal activity in human spatial navigation
Joshua J. Jacobs,Christoph T. Weidemann,Jonathan P. Miller,Alec Solway,John F. Burke,Xue-Xin Wei,Nanthia Suthana,Michael R. Sperling,Ashwini Sharan,Itzhak Fried,Itzhak Fried,Michael J. Kahana +11 more
TL;DR: Recording neuronal activity from neurosurgical patients performing a virtual-navigation task, it is identified cells exhibiting grid-like spiking patterns in the human brain, suggesting that humans and simpler animals rely on homologous spatial-coding schemes.
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Distinct Early Serological Signatures Track with SARS-CoV-2 Survival.
Caroline Atyeo,Caroline Atyeo,Stephanie Fischinger,Stephanie Fischinger,Tomer Zohar,Tomer Zohar,Matthew D. Slein,John F. Burke,Carolin Loos,Carolin Loos,Denise J. McCulloch,Kira L. Newman,Caitlin R Wolf,Jingyou Yu,Kiel Shuey,Jared Feldman,Blake M. Hauser,Timothy M. Caradonna,Aaron G. Schmidt,Todd J. Suscovich,Caitlyn Linde,Yongfei Cai,Dan H. Barouch,Edward T. Ryan,Richelle C. Charles,Douglas A. Lauffenburger,Helen Y. Chu,Galit Alter +27 more
TL;DR: It is demonstrated that early antigen-specific and qualitative features of SARS-CoV-2-specific antibodies, point to differences in disease trajectory, highlighting the potential importance of functional antigen- specific humoral immunity to guide patient care and vaccine development.
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Glucose Requirements Following Burn Injury: Parameters of Optimal Glucose Infusion and Possible Hepatic and Respiratory Abnormalities Following Excessive Glucose Intake
TL;DR: There appears to be a maximal rate of glucose infusion, beyond which physiologically significant increases in protein synthesis and direct oxidation of glucose cannot be expected, as indicated by increased rates of CO2 production during infusion as well as large fat deposits in the liver at autopsy in patients infused with large amounts of glucose.
Journal ArticleDOI
Synchronous and Asynchronous Theta and Gamma Activity during Episodic Memory Formation
John F. Burke,Kareem A. Zaghloul,Joshua J. Jacobs,Ryan B. Williams,Michael R. Sperling,Ashwini Sharan,Michael J. Kahana +6 more
TL;DR: It is suggested that network synchrony analyses, as used here, can help to distinguish between two major types of spectral modulations that reflect synchronous engagement of regional neurons with neighboring brain areas, and those that reflect either asynchronous modulations of neural activity or local synchrony accompanied by global disengagement from neighboring regions.
Journal ArticleDOI
Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality.
Tomer Zohar,Carolin Loos,Stephanie Fischinger,Caroline Atyeo,Chuangqi Wang,Matthew D. Slein,John F. Burke,Jingyou Yu,Jared Feldman,Blake M. Hauser,Timothy M. Caradonna,Aaron G. Schmidt,Yongfei Cai,Hendrik Streeck,Edward T. Ryan,Dan H. Barouch,Richelle C. Charles,Douglas A. Lauffenburger,Galit Alter +18 more
TL;DR: The early evolution of the humoral response was dissected in 193 hospitalized individuals ranging from moderate-to severe, highlighting distinct humoral trajectories associated with resolution of SARS-CoV-2 infection and the need for early functional humoral immunity.