J
John M. Hoffman
Researcher at Huntsman Cancer Institute
Publications - 244
Citations - 15982
John M. Hoffman is an academic researcher from Huntsman Cancer Institute. The author has contributed to research in topics: Positron emission tomography & Cancer. The author has an hindex of 62, co-authored 229 publications receiving 15277 citations. Previous affiliations of John M. Hoffman include University of Alabama at Birmingham & Case Western Reserve University.
Papers
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Journal ArticleDOI
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome.
Daniel H.S. Silverman,Gary W. Small,Carol Y Chang,Carolyn S. Lu,Michelle A. Kung de Aburto,Wei Chen,Johannes Czernin,Stanley I. Rapoport,Pietro Pietrini,Gene E. Alexander,Mark B. Schapiro,William J. Jagust,John M. Hoffman,Kathleen A. Welsh-Bohmer,Abass Alavi,Christopher M. Clark,Eric Salmon,Mony J. de Leon,R. Mielke,Jeffrey L. Cummings,Arthur P. Kowell,Sanjiv S. Gambhir,Carl K. Hoh,Michael E. Phelps +23 more
TL;DR: In patients presenting with cognitive symptoms of dementia, regional brain metabolism was a sensitive indicator of AD and of neurodegenerative disease in general and a negative PET scan indicated that pathologic progression of cognitive impairment during the mean 3-year follow-up was unlikely to occur.
Journal Article
Consensus Recommendations for the Use of 18F-FDG PET as an Indicator of Therapeutic Response in Patients in National Cancer Institute Trials
Lalitha K. Shankar,John M. Hoffman,Steve Bacharach,Michael M. Graham,Joel S. Karp,Adriaan A. Lammertsma,Steven M. Larson,David A. Mankoff,Barry A. Siegel,Annick D. Van den Abbeele,Jeffrey T. Yap,Daniel C. Sullivan +11 more
TL;DR: This paper presents a meta-modelling study of the response of positron emission tomography (PET) to radiolysis (radiolysis) and its applications to nuclear medicine and Radiology.
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Progress and Promise of FDG-PET Imaging for Cancer Patient Management and Oncologic Drug Development
Gary J. Kelloff,John M. Hoffman,Bruce E. Johnson,Howard I. Scher,Barry A. Siegel,Edward Y. Cheng,Bruce D. Cheson,Joyce O'Shaughnessy,Kathryn Z. Guyton,David A. Mankoff,Lalitha K. Shankar,Steven M. Larson,Caroline C. Sigman,Richard L. Schilsky,Daniel C. Sullivan +14 more
TL;DR: Its potential to facilitate drug development in seven oncologic settings (lung, lymphoma, breast, prostate, sarcoma, colorectal, and ovary) is addressed and its potential as a surrogate of clinical benefit is addressed.
Journal Article
Performance characteristics of a whole-body PET scanner.
Timothy R. DeGrado,Timothy G. Turkington,J. J. Williams,Charles W. Stearns,John M. Hoffman,R E Coleman +5 more
TL;DR: The results show the performance of the newly designed whole-body PET scanner to be well suited for clinical and research applications.
Journal ArticleDOI
Neural Activity Related to Drug Craving in Cocaine Addiction
Clinton D. Kilts,Julie B. Schweitzer,Colin K. Quinn,Colin K. Quinn,Robin E. Gross,Tracy L. Faber,Faheemah Muhammad,Timothy D. Ely,John M. Hoffman,Karen Drexler +9 more
TL;DR: The collected findings suggest the craving-related activation of a network of limbic, paralimbic, and striatal brain regions, including structures involved in stimulus-reward association (amygdala), incentive motivation (subcallosal gyrus/nucleus accumbens), and anticipation (anterior cingulate cortex).