J
John P. Iredale
Researcher at University of Bristol
Publications - 221
Citations - 26200
John P. Iredale is an academic researcher from University of Bristol. The author has contributed to research in topics: Hepatic stellate cell & Fibrosis. The author has an hindex of 77, co-authored 221 publications receiving 23394 citations. Previous affiliations of John P. Iredale include University College London & University of Cambridge.
Papers
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Journal ArticleDOI
Tissue Inhibitor of Metalloproteinase-1 Inhibits Apoptosis of Rat and Human Hepatic Stellate Cells In Vitro
TL;DR: A further finding in this study is that sustained apoptosis of HSC accompanies recovery from fibrosis, and has highlighted the role of TIMP-1 and -2 in HSC proliferation, survival and apoptosis.
Patent
Polymers for growing cells
TL;DR: In this article, a polyurethane polymer substrate for attachment and functioning of hepatocyte and hepatocyte-like cells is presented, and the polymer substrate is used to attach and activate the cells.
Gliotoxin stimulates the apoptosis of rat and human hepatic stellate cells in vitro.
Matthew Christopher Wright,R. Issa,John N. Primrose,Michael J. P. Arthur,John P. Iredale,Derek A. Mann +5 more
Journal ArticleDOI
Peer review: a flawed but essential process.
Journal ArticleDOI
Relaxin is a renal vasodilator in experimental models of cirrhosis and a potential novel therapy for hepatorenal syndrome in man
Victoria K. Snowdon,Antonella Pellicoro,Prakash Ramachandran,William Mungall,Maurits A. Jansen,Ross J. Lennen,Rebecca L. Aucott,Timothy J. Kendall,Jeremy Hughes,John P. Iredale,Jonathan A. Fallowfield +10 more
TL;DR: In this article, the effect of relaxin on renal blood flow and glomerular filtration rate (GFR) was investigated in male rats with 16 weeks of carbon tetrachloride and decompensated biliary cirrhosis.