J
John P. Plastaras
Researcher at University of Pennsylvania
Publications - 14
Citations - 217
John P. Plastaras is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Radiation therapy & Interquartile range. The author has an hindex of 7, co-authored 14 publications receiving 126 citations.
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Journal ArticleDOI
Early Changes in Cardiovascular Biomarkers with Contemporary Thoracic Radiation Therapy for Breast Cancer, Lung Cancer, and Lymphoma.
Biniyam G. Demissei,Gary M. Freedman,Steven J. Feigenberg,John P. Plastaras,Amit Maity,Amanda M. Smith,Caitlin McDonald,Karyn Sheline,Charles B. Simone,Charles B. Simone,Lilie L. Lin,Joseph R. Carver,Peter Liu,Liyong Zhang,Justin E. Bekelman,Bonnie Ky +15 more
TL;DR: Contemporary thoracic RT induces acute abnormalities in vascular and inflammatory biomarkers that are associated with radiation dose-volume metrics, particularly in lung cancer and mediastinal lymphoma, and were significantly associated with post-RT PIGF and GDF-15 levels in multivariable linear regression models.
Journal ArticleDOI
Technical Note: More accurate and efficient segmentation of organs-at-risk in radiotherapy with convolutional neural networks cascades.
Kuo Men,Kuo Men,H. Geng,Chingyun Cheng,Haoyu Zhong,Mi Huang,Yong Fan,John P. Plastaras,Alexander Lin,Ying Xiao +9 more
TL;DR: The proposed two-step network demonstrated superior performance by reducing the input region and potentially can be an effective segmentation method that provides accurate and consistent delineation with reduced clinician interventions for clinical applications as well as for quality assurance of a multicenter clinical trial.
Journal ArticleDOI
Clinical Outcomes of the HIV Protease Inhibitor Nelfinavir With Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non–Small Cell Lung Cancer: A Phase 1/2 Trial
Ramesh Rengan,Ramesh Rengan,Rosemarie Mick,Daniel A. Pryma,Lilie Leming Lin,John P. Christodouleas,John P. Plastaras,Charles B. Simone,Anjali K. Gupta,Tracey L. Evans,James P. Stevenson,Corey J. Langer,John C. Kucharczuk,Joseph S. Friedberg,Sarah Lam,Dana Patsch,Stephen M. Hahn,Amit Maity +17 more
TL;DR: It is suggested that nelfinavir administered with concurrent CT-RT is associated with acceptable toxic effects and a promising objective response rate, local failure, progression-free survival, and overall survival in unresectable LA-NSCLC.
Journal ArticleDOI
Pencil Beam Scanning Proton Beam Chemoradiation Therapy With 5-Fluorouracil and Mitomycin-C for Definitive Treatment of Carcinoma of the Anal Canal: A Multi-institutional Pilot Feasibility Study
Jennifer Y. Wo,John P. Plastaras,James M Metz,Wenqing Jiang,Beow Y. Yeap,Lorraine C. Drapek,Judith Adams,Christian V. Baglini,David P. Ryan,Janet E. Murphy,Aparna Raj Parikh,Jill N. Allen,Jeffrey W. Clark,Lawrence S. Blaszkowsky,Thomas F. DeLaney,Edgar Ben-Josef,Theodore S. Hong +16 more
TL;DR: PBS-PT was found to be feasible in a prospective, multi-institutional pilot study evaluating the feasibility of definitive concurrent chemoradiation with PBS-PT in combination with 5-FU and MMC for carcinoma of the anal canal.
Proceedings ArticleDOI
Cherenkov imaging for Total Skin Electron Therapy (TSET)
Y. Xie,Heather Petroccia,Amit Maity,Tianshun Miao,Yihua Zhu,Petr Bruza,Brian W. Pogue,Jacqueline M. Andreozzi,John P. Plastaras,Lei Dong,Timothy C. Zhu +10 more
TL;DR: Patients undergoing TSET in various conditions (whole body and half body) were imaged and analyzed, and the viability of the system to provide clinical feedback was established.