J
John R. Hurst
Researcher at University College London
Publications - 344
Citations - 16669
John R. Hurst is an academic researcher from University College London. The author has contributed to research in topics: COPD & Exacerbation. The author has an hindex of 51, co-authored 281 publications receiving 12644 citations. Previous affiliations of John R. Hurst include Royal College of Physicians & Boston University.
Papers
More filters
Journal ArticleDOI
Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease
John R. Hurst,Jørgen Vestbo,Jørgen Vestbo,Antonio Anzueto,Nicholas Locantore,Hana Müllerová,Ruth Tal-Singer,Bruce E. Miller,David A. Lomas,Alvar Agusti,William MacNee,Peter M.A. Calverley,Stephen I. Rennard,Emiel F.M. Wouters,Jadwiga A. Wedzicha +14 more
TL;DR: Although exacerbations become more frequent and more severe as COPD progresses, the rate at which they occur appears to reflect an independent susceptibility phenotype, which has implications for the targeting of exacerbation-prevention strategies across the spectrum of disease severity.
Journal ArticleDOI
Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease.
TL;DR: Patient recognition of exacerbation symptoms and prompt treatment improves exacerbation recovery, reduces risks of hospitalization, and is associated with a better health-related quality of life.
Journal ArticleDOI
'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19.
Swapna Mandal,Joseph Barnett,Simon E. Brill,Jeremy S. Brown,Emma K Denneny,S.S. Hare,Melissa Heightman,Toby Hillman,Joseph Jacob,Hannah Jarvis,Marc Lipman,S. B. Naidu,Arjun Nair,Joanna C. Porter,Gillian S. Tomlinson,John R. Hurst +15 more
TL;DR: Systematic follow-up after hospitalisation with COVID-19 identifies the trajectory of physical and psychological symptom burden, recovery of blood biomarkers and imaging which could be used to inform the need for rehabilitation and/or further investigation.
Journal ArticleDOI
Prevalence, Severity and Mortality associated with COPD and Smoking in patients with COVID-19: A Rapid Systematic Review and Meta-Analysis.
Jaber S Alqahtani,Jaber S Alqahtani,Tope Oyelade,Abdulelah M Aldhahir,Abdulelah M Aldhahir,Saeed M Alghamdi,Saeed M Alghamdi,Mater Almehmadi,Abdullah S. Alqahtani,Shumonta Quaderi,Swapna Mandal,Swapna Mandal,John R. Hurst +12 more
TL;DR: Although COPD prevalence in CO VID-19 cases was low in current reports, COVID-19 infection was associated with substantial severity and mortality rates in COPD, and effective preventive measures are required in patients and current smokers.
Journal ArticleDOI
Airway and systemic inflammation and decline in lung function in patients with COPD.
Gavin C. Donaldson,Terence A. R. Seemungal,Irem Patel,Angshu Bhowmik,Tom Wilkinson,John R. Hurst,Peter MacCallum,Jadwiga A. Wedzicha +7 more
TL;DR: In COPD, airway and systemic inflammatory markers increase over time; high levels of these markers are associated with a faster decline in lung function, and patients whose IL-6 exceeded the group median had a faster FEV1%Pred decline.