John S. Thornton

TL;DR: Evaluating the pathological substrate of high field MRI in post-mortem (PM) spinal cord of patients with MS found myelin content and axonal density correlated strongly with MTR, T1, PD, and diffusion anisotropy, but only moderately with T2 and weakly with the apparent diffusion coefficient.

TL;DR: In pathologically distinct neuromuscular disorders, the comparative responsiveness of MRI outcome measures over 1 year, the validity ofMRI outcome measures by cross-sectional correlation against functionally relevant clinical measures, and the sensitivity of specific MRI indices to early muscle water changes before intramuscular fat accumulation beyond the healthy control range are determined.

TL;DR: Resting state fMRI and dynamic causal modelling are used to study changes in ‘effective’ connectivity within the basal ganglia and implicate subthalamic afferents and the direct pathway in the clinical response.

TL;DR: It cannot be assumed that cerebral artery diameter is constant, especially during alterations of inspired oxygen partial pressure, and that transcranial 2D ultrasound is a technique that can be used at the bedside or in the remote setting to assess MCA caliber.

TL;DR: Solitaire thrombectomy for large vessel ischemic stroke was safe and highly effective with substantially reduced disability and benefits were consistent in all prespecified subgroups.