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Andrew M. Demchuk
Researcher at University of Calgary
Publications - 573
Citations - 48671
Andrew M. Demchuk is an academic researcher from University of Calgary. The author has contributed to research in topics: Stroke & Modified Rankin Scale. The author has an hindex of 92, co-authored 526 publications receiving 39252 citations. Previous affiliations of Andrew M. Demchuk include Autonomous University of Barcelona & Emory University.
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Journal ArticleDOI
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
Mayank Goyal,Bijoy K Menon,Wim H. van Zwam,Diederik W.J. Dippel,Peter Mitchell,Andrew M. Demchuk,Antoni Dávalos,Charles B. L. M. Majoie,Aad van der Lugt,Maria Angeles De Miquel,Geoffrey A. Donnan,Yvo B.W.E.M. Roos,Alain Bonafe,Reza Jahan,Hans-Christoph Diener,Lucie A. van den Berg,Elad I. Levy,Olvert A. Berkhemer,Vitor Mendes Pereira,Jeremy L. Rempel,Mónica Millán,Stephen M. Davis,Daniel Roy,John Thornton,Luis San Roman,Marc Ribo,Debbie Beumer,Bruce Stouch,Scott Brown,Bruce C.V. Campbell,Robert J. van Oostenbrugge,Jeffrey L. Saver,Michael D. Hill,Tudor G Jovin +33 more
TL;DR: Endovascular thrombectomy is of benefit to most patients with acute ischaemic stroke caused by occlusion of the proximal anterior circulation, irrespective of patient characteristics or geographical location, and will have global implications on structuring systems of care to provide timely treatment.
Journal ArticleDOI
Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging
Gregory W. Albers,Michael P. Marks,Stephanie Kemp,Soren Christensen,Jenny P Tsai,Santiago Ortega-Gutierrez,Ryan A McTaggart,Michel T. Torbey,May Kim-Tenser,Thabele M Leslie-Mazwi,Amrou Sarraj,Scott E. Kasner,Sameer A. Ansari,Sharon D. Yeatts,Scott Hamilton,Michael Mlynash,Jeremy J Heit,Greg Zaharchuk,Sun Kim,Janice Carrozzella,Yuko Y. Palesch,Andrew M. Demchuk,Roland Bammer,Philip W. Lavori,Joseph P. Broderick,Maarten G Lansberg +25 more
TL;DR: Endovascular thrombectomy for ischemic stroke 6 to 16 hours after a patient was last known to be well plus standard medical therapy resulted in better functional outcomes than standard medical Therapy alone among patients with proximal middle‐cerebral‐artery or internal‐carotid‐arterY occlusion and a region of tissue that was ischeMIC but not yet infarcted.
Journal ArticleDOI
Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy
TL;DR: This CT score is simple and reliable and identifies stroke patients unlikely to make an independent recovery despite thrombolytic treatment as well as primary outcomes, including symptomatic intracerebral haemorrhage and 3-month functional outcome.
Journal ArticleDOI
Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke
Joseph P. Broderick,Yuko Y. Palesch,Andrew M. Demchuk,Sharon D. Yeatts,Pooja Khatri,Michael D. Hill,Edward C. Jauch,Tudor G Jovin,Bernard Yan,Frank L. Silver,Ruediger von Kummer,Carlos A. Molina,Bart M. Demaerschalk,Ronald F. Budzik,Wayne M. Clark,Osama O. Zaidat,Tim W. Malisch,Mayank Goyal,Wouter J. Schonewille,Mikael Mazighi,Stefan T. Engelter,Craig S. Anderson,Judith Spilker,Janice Carrozzella,Karla J Ryckborst,L. Scott Janis,Renee H Martin,Lydia D. Foster,Thomas A. Tomsick +28 more
TL;DR: The trial showed similar safety outcomes and no significant difference in functional independence with endovascular therapy after intravenous t-PA, as compared with intravenoust-PA alone.
Journal ArticleDOI
Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis
Jeffrey L. Saver,Mayank Goyal,Aad van der Lugt,Bijoy K Menon,Charles B. L. M. Majoie,Diederik W.J. Dippel,Bruce C.V. Campbell,Raul G Nogueira,Andrew M. Demchuk,Alejandro Tomasello,Pere Cardona,Thomas Devlin,Donald Frei,Richard du Mesnil de Rochemont,Olvert A. Berkhemer,Tudor G Jovin,Adnan H. Siddiqui,Wim H. van Zwam,Stephen M. Davis,Carlos Castaño,Biggya L. Sapkota,Puck S.S. Fransen,Carlos A. Molina,Robert J. van Oostenbrugge,Ángel Chamorro,Hester F. Lingsma,Frank L. Silver,Geoffrey A. Donnan,Ashfaq Shuaib,Scott Brown,Bruce Stouch,Peter Mitchell,Antoni Dávalos,Yvo B.W.E.M. Roos,Michael D. Hill +34 more
TL;DR: The period in which endovascular thrombectomy is associated with benefit, and the extent to which treatment delay is related to functional outcomes, mortality, and symptomatic intracranial hemorrhage are characterized are characterized.