J
José A. Luchsinger
Researcher at Columbia University
Publications - 267
Citations - 21579
José A. Luchsinger is an academic researcher from Columbia University. The author has contributed to research in topics: Dementia & Risk factor. The author has an hindex of 68, co-authored 231 publications receiving 19153 citations. Previous affiliations of José A. Luchsinger include Columbia University Medical Center & University of California, Davis.
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Journal ArticleDOI
The cross-sectional association of renal dysfunction with tests of cognition in middle-aged adults with early type 2 diabetes the grade study
Joshua I. Barzilay,Joshua I. Barzilay,Naji Younes,Rodica Pop-Busui,Hermes Florez,Elizabeth R. Seaquist,Corinna Falck-Ytter,José A. Luchsinger +7 more
TL;DR: In type 2 diabetes of short duration, there are already subtle deficiencies in markers of cognition in association with renal disease in middle aged adults.
Journal ArticleDOI
P4-565: intact global cognitive and olfactory abilities predict lack of transition to dementia
Davangere P. Devanand,Seonjoo Lee,José A. Luchsinger,Edward D. Huey,Nicole Schupf,Jennifer J. Manly,Yaakov Stern,William C. Kreisl,Richard Mayeux +8 more
Posted ContentDOI
Diabetes and dementia incidence in Latin America; a 10/66 population-based cohort study
Aquiles Salas,Daisy Acosta,Mariella Guerra,Yueqin Huang,Ivonne Z. Jimenez-Velazquez,Juan J. Llibre Rodriguez,Ana Luisa Sosa,Michael E. Dewey,Ciro Gaona,Maëlenn Guerchet,Loida M. Gonzalez,Zhaorui Liu,José A. Luchsinger,A. M. Lopez Medina,Rosa María Salinas,Martin Prince +15 more
TL;DR: Diabetes, particularly when poorly controlled, may increase dementia risk, and there is considerable scope for improved detection and control of diabetes among older people in these settings, and hence an opportunity to carry out proof of concept prevention trials.
Journal ArticleDOI
Association of Metformin With the Development of Age-Related Macular Degeneration.
Amitha Domalpally,Samuel A. Whittier,Qing Pan,Dana Dabelea,Christine Darwin,William C. Knowler,Christine G. Lee,José A. Luchsinger,Neil H. White,Emily Y. Chew +9 more
TL;DR: The Diabetes Prevention Program Outcomes Study as discussed by the authors investigated the association between metformin use and age-related macular degeneration (AMD) in a large multicenter randomized clinical trial.
Journal ArticleDOI
Development, initial validation, and application of a visual read method for [18F]MK‐6240 tau PET
Joanna L. Shuping,Dawn C. Matthews,Katarzyna Adamczuk,David Scott,Christopher C. Rowe,William C. Kreisl,Sterling C. Johnson,Ana S. Lukic,Keith A. Johnson,Pedro Rosa-Neto,Randolph D. Andrews,Koen Van Laere,Lindsay Cordes,Larry Ward,Claire L. Wilde,Jerome Barakos,Derk D. Purcell,Davangere P. Devanand,Yaakov Stern,José A. Luchsinger,Cyrille Sur,Julie C. Price,Adam M. Brickman,William E. Klunk,Adam L. Boxer,Sulantha Mathotaarachchi,Patrick J. Lao,Jeffrey L. Evelhoch +27 more
TL;DR: In this article , the positron emission tomography (PET) radiotracer [18F]MK•6240 exhibits high specificity for neurofibrillary tangles (NFTs) of tau protein in Alzheimer's disease (AD), high sensitivity to medial temporal and neocortical NFTs, and low within brain background.